ESTRUMATE SYNTHETIC PROSTAGLANDIN FOR CATTLE AND HORSES

Negara: Australia

Bahasa: Inggris

Sumber: APVMA (Australian Pesticides and Veterinary Medicines Authority)

Bahan aktif:

CLOPROSTENOL AS THE SODIUM SALT

Tersedia dari:

INTERVET AUSTRALIA PTY LIMITED

INN (Nama Internasional):

cloprostenol as Na salt(250ug/mL)

Bentuk farmasi:

PARENTERAL LIQUID/SOLUTION/SUSPENSION

Komposisi:

CLOPROSTENOL AS THE SODIUM SALT PROSTAGLANDIN Active 250.0 ug/ml

Unit dalam paket:

10 x 20mL; 100mL; 20mL

Kelas:

VM - Veterinary Medicine

Diproduksi oleh:

INTERVET AUSTRALIA

Kelompok Terapi:

CATTLE | HORSE | BEEF | BOS INDICUS | BOS TAURUS | BOVINE | BUFFALO | BULL | BULLOCK | CALF | COLT | COW | DAIRY COW | DONKEY |

Area terapi:

ENDOCRINE SYSTEM

Indikasi Terapi:

BOVINE OESTRUS CYCLE | EQUINE OESTRUS CYCLE | CTRL OF OESTRUS REL.BEHAVIOUR

Ringkasan produk:

Poison schedule: 4; Withholding period: WHP: MEAT: (CATTLE HORSES): DO NOT US E less than one day before slaughter fo r human consumption. MILK: NIL.; Host/pest details: CATTLE: [BOVINE OESTRUS CYCLE]; HORSE: [EQUINE OESTRUS CYCLE]; A luteolytic agent for clinical use and the control of the bovine and equine oestrus cycles.Should not be administered to pregnant animals where the foetus is not to be aborted. Care should be taken when handling this product especially by women of child bearing age and also by asthmatics.

Status otorisasi:

Registered

Tanggal Otorisasi:

2023-07-01

Selebaran informasi

ESTRUMATE SYNTHETIC PROSTAGLANDIN FOR CATTLE AND HORSES
36076/107149
Product Name:
APVMA Approval No:
Label Name:
ESTRUMATE SYNTHETIC PROSTAGLANDIN FOR CATTLE AND HORSES
Signal Headings:
PRESCRIPTION ANIMAL REMEDY
KEEP OUT OF REACH OF CHILDREN
FOR ANIMAL TREATMENT ONLY
Constituent
Statements:
250 ug/ml CLOPROSTENOL AS THE SODIUM SALT
Claims:
A luteolytic agent for clinical use and the control of the bovine and
equine oestrous cycles.
ESTRUMATE a synthetic prostaglandin analogue for use in cattle and
horses, is
structurally related to Prostaglandin F2a (PGF2a). Each mL of the
colourless aqueous
solution contains 263ug of cloprostenol sodium equivalent to 250ug
cloprostenol. The
solution also contains 2% benzyl alcohol Ph. Eur. as a bactericide.
Action: ESTRUMATE is a potent luteolytic agent, i.e. it causes
functional and morphological
regression of the corpus luteum (luteolysis) in a variety of
circumstances. Luteolysis is
usually followed by return to oestrus two to four days after
treatment, and normal ovulation.
Net Contents:
10 x 20mL
100mL
20mL
Directions for Use:
For use by or under direction of a registered veterinarian
DIRECTIONS FOR USE
Contraindications:
ESTRUMATE should not be administered to pregnant animals where the
foetus is not to be
aborted, since luteolysis at some stages of gestation will result in
the loss of the foetus.
ESTRUMATE should not be administered by intravenous injection.
Side Effects:
Note: There is a refractory period of four to five days after
ovulation when cattle are
insensitive to the luteolytic effect of prostaglandins. ESTRUMATE has
a good safety margin
and does not impair fertility. No deleterious effects have been
reported on the progeny
conceived at the oestrus following treatment. RLP APPROVED
In cattle adverse reactions have not been seen at up to 80 times the
effective
recommended dose (500μg). The only clinically apparent effect was
mild and transient
diarrhoea.
In horses adverse reactions including sweating (occurring within about
20 minutes of
treatment), increased

Karakteristik produk

PRODUCT NAME: ESTRUMATE SYNTHETIC PROSTAGLANDIN FOR CATTLE
AND HORSES
MATERIAL SAFETY DATA SHEET
THIS REVISION ISSUED: AUGUST, 2009
PAGE: 1 OF 6
MATERIAL SAFETY DATA SHEET
Issued by: Intervet Australia Pty Limited Phone: [phone]
(Business Hours)
Poisons Information Centre: 13 11 26 from anywhere in Australia, (0800
764 766 in New Zealand)
SUBSTANCE:
Water solution of Cloprostenol as the sodium salt.
TRADE NAME:
ESTRUMATE SYNTHETIC PROSTAGLANDIN FOR CATTLE AND HORSES
RECOMMENDED USE:
A luteolytic agent for clinical use and the control of the bovine and
equine oestrus cycles.
APVMA NO:
36076
CREATION DATE:
August, 2009
THIS VERSION ISSUED:
August, 2009
and is valid for 5 years from this date.
STATEMENT OF HAZARDOUS NATURE:
THIS PRODUCT IS CLASSIFIED AS:
Not classified as hazardous according to the criteria of SWA.
Not a Dangerous Good according to the Australian Dangerous Goods (ADG)
Code.
RISK PHRASES:
Not Hazardous - No criteria found.
SAFETY PHRASES:
S36, S24/25. Wear suitable protective clothing. Avoid contact with
skin and eyes.
SUSDP CLASSIFICATION:
S4
ADG CLASSIFICATION:
None allocated. Not a Dangerous Good under the ADG Code.
UN NUMBER:
None allocated
PHYSICAL DESCRIPTION & COLOUR:
Clear colourless aqueous solution.
ODOUR:
No data.
MAJOR HEALTH HAZARDS:
no significant risk factors have been found for this product. This is
a physiologically active
product and so contact should be minimised, especially if the user is
taking a form of medication, as interactions can
sometimes give unexpected and undesired results.
Contains Cloprostenol Sodium which is a synthetic prostaglandin of the
F
2
D
type, and is a potent luteolytic agent.
ESTRUMATE can be absorbed through the skin and therefore, care should
be taken when handling this product,
especially by women of child bearing age and also by asthmatics.
INHALATION:
SHORT TERM EXPOSURE:
Available data indicates that this product is not harmful. In addition
product is unlikely to
cause any discomfort or irritation.
LONG TERM EXPOSURE:
No data for health effects