Duromine

Negara: Australia

Bahasa: Inggris

Sumber: Department of Health (Therapeutic Goods Administration)

Bahan aktif:

Phentermine

Tersedia dari:

iNova Pharmaceuticals Australia Pty Ltd

Kelas:

Medicine Listed (Export Only)

Selebaran informasi

DUROMINE™

_(DURE-O-MEAN)_
_Phentermine (fen-ter-mean)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Duromine. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist. If you need any more
information about Duromine please
ask your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risk of you taking Duromine
against the benefits it can have for
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may want to read it again.
YOUR MEDICINE
The name of your medicine is
Duromine. Duromine capsules
contain the active ingredient,
phentermine. Phentermine is
combined with a resin which slowly
releases the phentermine so the effect
of Duromine lasts all day.
WHAT DUROMINE IS
USED FOR
This medicine is used to reduce body
weight in obese or overweight
patients. Your doctor will determine
if you are overweight enough to use
Duromine. Duromine works by
directly affecting the area of the brain
that controls your appetite making
you feel less hungry.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS MEDICINE
HAS BEEN PRESCRIBED FOR YOU.
Your doctor may have prescribed it
for another reason.
Duromine should be used as a part of
an overall weight management plan
which should include a medically
controlled diet and exercise program.
Duromine is available only with a
doctor's prescription.
DO NOT GIVE IT TO ANYONE ELSE EVEN IF
THEIR CONDITION IS THE SAME AS
YOURS.
Your doctor may prescribe Duromine
for another purpose. If you are not
sure why you are taking this
medicine ask your doctor.
BEFORE YOU TAKE
DUROMINE
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE DUROMINE IF YOU HAVE
AN ALLERGY TO:
•
any medicine containing
phentermine
•
any of the ingredients listed at the
end of this leaflet
•
any other similar medicines used
to reduce weight
Some of the symptoms of an allergic
re

Karakteristik produk

DUROMINE™
_(Phentermine)_
_ _PRODUCT INFORMATION
NAME OF THE DRUG
Phentermine (phenyl tertiary butylamine, C
10
H
15
N)
           H   CH
3

⏐   ⏐

⎯C⎯C NH
2

⏐    ⏐
           H   CH
3
DESCRIPTION
Each Duromine capsule contains phentermine as an ion-exchange resin
complex equivalent to 15, 30 or
40 mg phentermine depending on strength.  The ion-exchange resin is
quite stable, highly insoluble and
without pharmacological effect until it reacts with cations (hydrogen,
potassium, sodium etc) present in
the gastrointestinal fluids.  Phentermine is then released from the
resin complex at a rate dependent on
the total concentration of these cations.  Since this concentration
is fairly constant throughout the entire
gastrointestinal tract, continuous and controlled ionic release occurs
over a 10 to 14 hour period.
Each Duromine capsule also contains, as inactive ingredients, lactose,
liquid paraffin, magnesium
stearate, gelatin, titanium dioxide and iron oxide black (CI 77499)
.  In addition Duromine 15 also
contains brilliant blue FCF (CI 42090), iron oxide yellow (CI 77492);
Duromine 30 also contains iron
oxide red (CI 77491); Duromine 40 also contains erythrosine (CI
45430), sunset yellow FCF
(CI 15985).  Duromine capsules are gluten-free_._
PHARMACOLOGY
PHARMACODYNAMIC PROPERTIES
Phentermine is a sympathomimetic amine with significant anorectic
activity in animal models.  Its
appetite suppressant effect is generally considered to be exerted
through the hypothalamus, but it is not
certain that this is the only effect related to weight loss.
 Phentermine has major effects on the
dopaminergic and noradrenergic nervous systems.  The cardiovascular
effects include a pressor
response and increase in heart rate and force of contraction.
PHARMACOKINETIC PROPERTIES 
Absorption of phentermine is almost complete.  The rate of