Dexon Injection

Negara: Bangladesh

Bahasa: Inggris

Sumber: DGDA (Directorate General of Drug Administration)

Bahan aktif:

Dexamethasone Sodium Phosphate

Tersedia dari:

Ibn Sina Pharmaceutical Ind. Ltd.

INN (Nama Internasional):

Dexamethasone Sodium Phosphate

Dosis:

5 mg/ml

Bentuk farmasi:

Injection

Selebaran informasi

DEXON INJECTION
Dexamethasone
COMPOSITION
DEXON INJECTION: Each ml ampoule contains Dexamethasone Sodium
Phosphate BP 5mg.
DESCRIPTION
Dexon Injection is a synthetic long-acting glucocorticoid that
depresses formation, release and activity
of endogenous mediators of inflammation including prostaglandins,
kinins, histamine, liposomal enzymes
and complement system. Also modifies body's immune response.
INDICATION
Dexon Injections are used for the treatment of Various inflammatory
and autoimmune diseases e.g.:
Rheumatism, as pain, stiffness or limitation of motion, especially in
the joints and related structures,
including
muscles,
bursae,
tendons,
fibrous
tissue.
Collagen
disease,
as
lupus
erythematosus,
dermatomyositis,
sclerodema,
polyarteritis
nodosa,
thrombotic
purpurap
rheumatic
fever
and
rheumatoid
arthritis: Allergies, as status asthmaticus, bronchial asthma, contact
dermatitis, inflammatory processes of
the eye and its adnexa, severe hypersensitivity reactions to drugs or
insect stings, anaphylactic s hock,
impending allograft rejection. Acute ad renocortical insufficiency, as
in surgery, severe stress or trauma.
Besides Dexon is used as an adjunct in the control of cerebral oedema,
as anti-emetic in antineoplastic
regimens and for palliative treatment in terminal stages of neoplastic
disease.
DOSAGE AND ADMINISTRATION
The dosage of Dexon injection depends on the severity of the condition
and the response of the
patient. Undesirable effects may be minimized by lowering the dose or
adhering to an alternate day
dosage regimen. Acute condition, such as shock, severe allergic
reactions, fulminating infections, hepatic
coma and cerebral oedema, 8 - 40 mg by slow i.v. injection or
infusion. _ I_ntra-articular 2 - 4mg. Child -
(above acute conditions), 0.25 - 0.5 mg/kg body-wt. daily by slow i.v.
injection or infusion. Systemic:
IV/IM 0.5 to 9 mg/day. Cerebral Edema: IV 10 mg, then IM 4 mg 6 hr
until max response. Brain Tumors:
IV/IM 2 mg bid to tit. Unresponsive shock: IV 1 to 6 mg/kg as single
injection: or 40 m