Calcium Resonium

Negara: Australia

Bahasa: Inggris

Sumber: Department of Health (Therapeutic Goods Administration)

Bahan aktif:

Polystyrene sulfonate - calcium

Tersedia dari:

Catalent Australia Pty Ltd

Kelas:

Medicine Listed

Selebaran informasi

CALCIUM RESONIUM
®

_calcium polystyrene sulfonate_
CONSUMER MEDICINE INFORMATION (CMI)

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Calcium Resonium.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking this medicine
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
Keep this leaflet with the medicine.
You may need to read it again.
WHAT CALCIUM
RESONIUM IS USED FOR
Calcium Resonium is a type of
medicine used to help remove
excessive amounts of potassium from
the blood.
Calcium Resonium contains calcium
polystyrene sulfonate which contains
calcium atoms. This calcium is
swapped for potassium in the body,
particularly in the large intestine.
Calcium Resonium does not enter the
bloodstream from the intestine. It is
passed (with the potassium ions) with
the faeces.
Your doctor, however, may prescribe
Calcium Resonium for another
purpose.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY IT HAS BEEN
PRESCRIBED FOR YOU.
This medicine is only available with
a doctor's prescription.
BEFORE YOU TAKE IT
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE CALCIUM RESONIUM IF
YOU HAVE:
•
a bowel obstruction
•
high calcium levels in the blood
•
high levels of parathyroid
hormone (PTH)
•
multiple myeloma (a cancer of
the blood) or sarcoidosis (an
inflammatory disorder)
•
low levels of potassium (less than
5 mmol/L).
 DO NOT TAKE CALCIUM RESONIUM IF
YOU ARE ALLERGIC TO IT OR ANY OF THE
INGREDIENTS LISTED AT THE END OF THIS
LEAFLET.
 Some symptoms of an allergic
reaction include skin rash, itching,
shortness of breath or swelling of the
face, lips or tongue, which may cause
difficulty in swallowing or breathing.
 DO NOT GIVE ORAL CALCIUM
RESONIUM TO NEWBORN BABIES.
 Orally administered Calcium
Resonium has caused bowel
obstruction in newborns

Karakteristik produk

Calcium Resonium PI_ _
_#65687v3.0_ 
Page 1 

PRODUCT INFORMATION 
CALCIUM RESONIUM

NAME OF THE MEDICINE 
NON-PROPRIETARY NAME 
Calcium polystyrene sulfonate  
CHEMICAL STRUCTURE 

CAS NUMBER 
37286-92-3 
DESCRIPTION 
Calcium Resonium contains 99.93% calcium polystyrene sulfonate ground
and flavoured to 
a buff coloured fine powder with a vanilla odour and sweet
taste_.  _The sodium content of 
Calcium Resonium is less than 1 mg/g.  Calcium content is about 8%
w/w (1.6-2.4 mmol/g). 
Calcium Resonium also contains saccharin sodium and vanillin 
PHARMACOLOGY 
CLASS 
Calcium polystyrene sulfonate is a cation exchange resin prepared in
the calcium phase.  
SITE AND MODE OF ACTION 
Each gram of resin has a theoretical in vitro exchange capacity of
about 1.3 to 2 millimoles 
of potassium. However, in vivo, the actual amount of potassium bound
will be less than this. 
The resin is insoluble in water.  
PHARMACOKINETICS 
Absorption 
Calcium polystyrene sulfonate is not absorbed from the
gastrointestinal tract. 
Distribution 
Calcium polystyrene sulfonate removes potassium from the body by
exchanging it within the 
gut for calcium. For the most part, this action occurs in the large
intestine, which excretes 
potassium to a greater degree than does the small intestine. The
efficiency of potassium 
exchange is unpredictable and variable. The resin is not selective for
potassium. 
INDICATIONS 
Calcium Resonium is an ion-exchange resin.  It is recommended for
the treatment of 
hyperkalaemia associated with anuria and severe oliguria.   
CH
SO
3
CH
2
CH
SO
3
CH
2
-
-
_n_
_m_
Ca
++
Calcium Resonium PI_ _
_#65687v3.0_ 
Page 2 

It is also used to treat hyperkalaemia in patients requiring dialysis
and in patients on regular 
haemodialysis or on prolonged peritoneal dialysis. 
CONTRAINDICATIONS 
• 
History of hypersensitivity to polystyrene sulfonate resins.  
• 
Serum potassium levels less than 5 mmol/L. 
• 
Conditions associated with hypercalc