Negara: Amerika Serikat
Bahasa: Inggris
Sumber: NLM (National Library of Medicine)
ASCORBIC ACID (UNII: PQ6CK8PD0R) (ASCORBIC ACID - UNII:PQ6CK8PD0R)
American Regent, Inc.
ASCORBIC ACID
ASCORBIC ACID 500 mg in 1 mL
PRESCRIPTION DRUG
unapproved drug other
ASCORBIC ACID- ASCORBIC ACID INJECTION, SOLUTION AMERICAN REGENT, INC. _Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been_ _approved by FDA. For further information about unapproved drugs, click here._ ---------- ASCORBIC ACID INJECTION, USP RX ONLY FOR INTRAVENOUS, INTRAMUSCULAR OR SUBCUTANEOUS USE. CONTAINS NO PRESERVATIVES. DESCRIPTION Ascorbic Acid (vitamin C) is a water-soluble vitamin. It occurs as a white or slightly yellow crystal or powder with a slight acidic taste. It is an antiscorbutic product. On exposure to air and light it gradually darkens. In the dry state it is reasonably stable in air, but in solution it rapidly oxidizes. Ascorbic Acid is freely soluble in water; sparingly soluble in alcohol; insoluble in chloroform, ether, and benzene. The chemical name of Ascorbic Acid is L-ascorbic acid. The molecular formula is C H 0 and the molecular weight is 176.13. The structural formula is as follows: Ascorbic Acid Injection, USP is a clear, slightly yellow to yellow sterile solution of Ascorbic Acid in Water for Injection, for intravenous, intramuscular or subcutaneous use. Each mL contains Ascorbic Acid 500 mg, Edetate Disodium 0.025%, Water for Injection q.s. pH (range 5.5-7.0) adjusted with Sodium Bicarbonate. 6 8 6 CLINICAL PHARMACOLOGY In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration. Ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency Baca dokumen lengkapnya