ACEPROMAZINE MALEATE tablet

Negara: Amerika Serikat

Bahasa: Inggris

Sumber: NLM (National Library of Medicine)

Bahan aktif:

ACEPROMAZINE MALEATE (UNII: 37862HP2OM) (ACEPROMAZINE - UNII:54EJ303F0R)

Tersedia dari:

ZYVET ANIMAL HEALTH INC.

Rute administrasi :

ORAL

Jenis Resep:

PRESCRIPTION

Indikasi Terapi:

Indications: As an aid in tranquilization and as a preanesthetic agent in dogs. Acepromazine Maleate Tablets can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures. Contraindications: Phenothiazines may potentiate the toxicity of organophosphates. Therefore, do not use acepromazine maleate to control tremors associated with organic phosphate poisoning. Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. Do not use with procaine hydrochloride.

Ringkasan produk:

How Supplied: Acepromazine Maleate Tablets are available in 10 and 25 mg quarter-scored tablets and are supplied in bottles containing 100 and 500 tablets. NDC 86117-049-07 – 10 mg – 100 tablets NDC 86117-049-12 – 10 mg – 500 tablets NDC 86117-050-07 – 25 mg – 100 tablets NDC 86117-050-12 – 25 mg – 500 tablets Approved by FDA under ANADA # 200-757

Status otorisasi:

Abbreviated New Animal Drug Application

Karakteristik produk

ACEPROMAZINE MALEATE- ACEPROMAZINE MALEATE TABLET
ZYVET ANIMAL HEALTH INC.
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ACEPROMAZINE MALEATE TABLETS
For use in dogs only.
CAUTION: Federal law restricts this drug to use by or on the order of
a licensed
veterinarian.
DESCRIPTION: Acepromazine maleate, a potent neuroleptic agent with a
low order of
toxicity, is of particular value in the tranquilization of dogs. Its
rapid action and lack of
hypnotic effect are added advantages.
CHEMISTRY: 2-acetyl-10-(3-dimethylaminopropyl) phenothiazine hydrogen
maleate.
Acepromazine Maleate
MODE OF ACTION: Acepromazine maleate has a depressant effect on the
central
nervous system and therefore causes sedation, muscular relaxation and
a reduction in
spontaneous activity. It acts rapidly, exerting a prompt and
pronounced calming effect.
It is an effective preanesthetic agent and lowers the dosage
requirement of general
anesthetics.
INDICATIONS: As an aid in tranquilization and as a preanesthetic agent
in dogs.
Acepromazine Maleate Tablets can be used as an aid in controlling
intractable animals
during examination, treatment, grooming, x-ray and minor surgical
procedures.
DOSAGE AND ADMINISTRATION: Dogs: 0.25-1.0 mg/lb of body weight. Dosage
may be
repeated as required.
ANIMAL SAFETY: Acute and chronic toxicity studies have shown a very
low order of
toxicity for acepromazine maleate.
A safety study using elevated dosages of acepromazine maleate
demonstrated no
adverse reactions even when administered at three times the upper
limit of the
recommended daily dosage (3.0 mg/lb body weight). The clinical
observation for this
high dosage was mild depression which disappeared in most dogs 24
hours after
termination of dosing.
The only occurrence of adverse reaction during numerous clinical
trials was a very mild
respiratory distress (reverse sneeze) which was transient in nature
and had no effect on
the desired action of the drug.
CONTRAINDICATIONS: Phenothiazines may potentiate the toxicity of
organophosphates.
Therefore, do not use acepromazine maleate to control tremors