Country: Ամերիկայի Միացյալ Նահանգներ
language: անգլերեն
source: NLM (National Library of Medicine)
PRADOFLOXACIN (UNII: 6O0T5E048I) (PRADOFLOXACIN - UNII:6O0T5E048I)
Bayer HealthCare LLC Animal Health Division
PRADOFLOXACIN
PRADOFLOXACIN 25 mg in 1 mL
ORAL
PRESCRIPTION
VERAFLOX is indicated for the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of Pasteurella multocida, Streptococcus canis, Staphylococcus aureus, Staphylococcus felis, and Staphylococcus pseudintermedius. DO NOT USE IN DOGS. Pradofloxacin has been shown to cause bone marrow suppression in dogs. Dogs may be particularly sensitive to this effect, potentially resulting in severe thrombocytopenia and neutropenia. Quinolone-class drugs have been shown to cause arthropathy in immature animals of most species tested, the dog being particularly sensitive to this side effect. Pradofloxacin is contraindicated in cats with a known hypersensitivity to quinolones.
Code Number Bottle Size 84364593 15 mL 84364607 30 mL NADA 141-344, Approved by FDA 81083770 84364593 / 84364607, R.0 Made in Germany © 2012 Bayer HealthCare LLC Bayer, the Bayer Cross and VERAFLOX are registered trademarks of Bayer. VERAFLOX is protected by the following U.S. Patent 6,323,213. Bayer HealthCare LLC Animal Health Division Shawnee Mission, Kansas 66201, U.S.A. May, 2012
New Animal Drug Application
VERAFLOX- PRADOFLOXACIN SUSPENSION BAYER HEALTHCARE LLC ANIMAL HEALTH DIVISION ---------- VERAFLOX (PRADOFLOXACIN) ORAL SUSPENSION FOR CATS 25 MG/ML DO NOT USE IN DOGS. FEDERAL LAW PROHIBITS THE EXTRALABEL USE OF THIS DRUG IN FOOD-PRODUCING ANIMALS. CAUTION Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Pradofloxacin is a fluoroquinolone antibiotic and belongs to the class of quinoline carboxylic acid derivatives. Its chemical name is: 7-[(4aS) octahydro-6H-pyrrolo [3, 4-b] pyridine-6yl]-8-cyano-1- cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinoline carboxylic acid. Each mL of VERAFLOX Oral Suspension provides 25 mg of pradofloxacin. INDICATIONS VERAFLOX is indicated for the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of _Pasteurella multocida, Streptococcus canis, Staphylococcus aureus, Staphylococcus_ _felis, _and _Staphylococcus pseudintermedius._ DOSAGE AND ADMINISTRATION Shake well before use. To ensure a correct dosage, body weight should be determined as accurately as possible. The dose of VERAFLOX is 7.5 mg/kg (3.4 mg/lb) body weight once daily for 7 consecutive days. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Rinse syringe between doses. A sample of the lesion should be obtained for culture and susceptibility testing prior to beginning antibacterial therapy. Once results become available, continue with appropriate therapy. If acceptable response to treatment is not observed, or if no improvement is seen within 3 to 4 days, then the diagnosis should be re-evaluated and appropriate alternative therapy considered. CONTRAINDICATIONS ® DO NOT USE IN DOGS. PRADOFLOXACIN HAS BEEN SHOWN TO CAUSE BONE MARROW SUPPRESSION IN DOGS. DOGS MAY BE PARTICULARLY SENSITIVE TO THIS EFFECT, POTENTIALLY RESULTING IN SEVERE THROMBOCYTOPENIA AND NEUTROPENIA. Quinolone-class drugs have been shown to cause arthropathy in immature animals of most species tested, the dog being particularly sensitive to read_full_document