VAXCEL CEFOBACTAM-1G INJECTION

Երկիր: Մալայզիա

Լեզու: անգլերեն

Աղբյուրը: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ակտիվ բաղադրիչ:

SULBACTAM SODIUM; Sterile Cefoperazone Sodium

Հասանելի է:

KOTRA PHARMA (M) SDN. BHD.

INN (Միջազգային անվանումը):

SULBACTAM SODIUM; Sterile Cefoperazone Sodium

Միավորները փաթեթում:

1 gm mcg/mL; 1 gm mcg/mL

Պատրաստված է:

KOTRA PHARMA (M) SDN. BHD.

Տեղեկատվական թերթիկ

NONE
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Ապրանքի հատկությունները

CEFOBACTAM 1G
INJECTION COMPOSITION:
Each vial contains
Cefoperazone
Sodium
/
Sulbactam
Sodium
equivalent to Cefoperazone 500mg and Sulbactam
500mg. PRESENTATION:
White
or
off-white
powder
free
from
visible
contamination. Clear to pale yellow solution after
reconstitution. INDICATIONS:
_Monotherapy:_
Sulbactam
/
cefoperazone
is
indicated
for
the
treatment of the following infections when caused
by susceptible organism:
Respiratory
tract
infections
(upper
and
lower).
Urinary
tract
infections
(upper
and
lower).
Peritonitis.
Cholecystitis.
Cholangitis
and
other
intra-abdominal infections. Septicemia. Meningitis.
Skin and soft tissue infections. Bone and joint
infections.
Pelvic
Inflammatory
Disease.
Endometritis. Gonorrhea and other infections of the
genital tract.
_Combination Therapy:_
Because of the broad spectrum of the activity of
sulbactam/cefoperazone, most infections can be
treated
adequately
with
this
antibiotic
alone.
However, sulbactam / cefoperazone may be used
concomitantly
with
other
antibiotics
if
such
combinations are indicated. If an aminoglycoside is
used (see Interaction With Other Medicaments),
renal
function
should
be
monitored
during
the
course of therapy (see Recommended Dose Use in
Renal Function). PHARMACODYNAMICS:
The
antibacterial
component
of
sulbactam
/
cefoperazone is cefoperazone, a third generation
cephalosporin,
which
acts
against
sensitive
organisms during the stage of active multiplication
by inhibiting biosynthesis of cell wall mucopeptide.
Sulbactam
does
not
possess
any
useful
antibacterial activity, except against Neisseriaceae
and Acinetobacter. However, biochemical studies
with cell-free bacterial systems have shown it to be
an
irreversible
inhibitor
of
most
important
b
-
lactamases
produced
by
b-lactam
antibiotic
-
resistant organisms.
The
potential
for
sulbactam
preventing
the
destruction of penicillins and cephalosporins by
resistant
organisms
was
confirmed
in
whole-organism studies using resistant strains in
which sulbactam exhibited marked synergy with
penicillins and cep