Երկիր: Ամերիկայի Միացյալ Նահանգներ
Լեզու: անգլերեն
Աղբյուրը: NLM (National Library of Medicine)
METHYLTESTOSTERONE (UNII: V9EFU16ZIF) (METHYLTESTOSTERONE - UNII:V9EFU16ZIF)
Valeant Pharmaceuticals North America LLC
METHYLTESTOSTERONE
METHYLTESTOSTERONE 10 mg
PRESCRIPTION DRUG
Abbreviated New Drug Application
TESTRED C-III- METHYLTESTOSTERONE CAPSULE VALEANT PHARMACEUTICALS NORTH AMERICA LLC ---------- TESTRED C-III BRAND OF METHYLTESTOSTERONE CAPSULES USP, 10 MG RX ONLY DESCRIPTION The androgens are steroids that develop and maintain primary and secondary male sex characteristics. Androgens are derivatives of cyclopentanoperhydrophenanthrene. Endogenous androgens are C-19 steroids with a side chain at C-17, and with two angular methyl groups. Testosterone is the primary endogenous androgen. In their active form, all drugs in the class have a 17-beta hydroxy group. 17- alpha alkylation (methylTESTOSTERone) increases the pharmacologic activity per unit weight compared to testosterone when given orally. MethylTESTOSTERone, a synthetic derivative of testosterone, is an androgenic preparation given by the oral route in a capsule form. Each capsule contains 10 mg of MethylTESTOSTERone USP. It has the following structural formula: C H O M.W. 302.46 17-β-hydroxy-17-methylandrost-4-en-3-one MethylTESTOSTERone occurs as white or creamy white crystals or powder, which is soluble in various organic solvents but is practically insoluble in water. Each capsule, for oral administration, contains 10 mg of methylTESTOSTERone. In addition, each capsule contains the following inactive ingredients: Corn starch NF, Gelatin NF, FD&C Blue #1, FD&C Red #40. CLINICAL PHARMACOLOGY Endogenous androgens are responsible for the normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include the growth and maturation ® 20 30 2 of prostate, seminal vesicles, penis, and scrotum; the development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, alterations in body musculature, and fat distribution. Drugs in this class also cause retention of nitrogen, sodium, potassium, phosphorus, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism Կարդացեք ամբողջական փաստաթուղթը