Երկիր: Ավստրալիա
Լեզու: անգլերեն
Աղբյուրը: Department of Health (Therapeutic Goods Administration)
Sertraline hydrochloride
Pfizer Australia Pty Ltd
Medicine Registered
SERTRALINE PFIZER ® _Sertraline (sir-tra-leen) hydrochloride_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Sertraline Pfizer. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Sertraline Pfizer against the benefits it is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT SERTRALINE PFIZER IS USED FOR Sertraline Pfizer is used to treat depression and conditions called obsessive compulsive disorder (OCD), panic disorder, social phobia (social anxiety disorder) and premenstrual dysphoric disorder (PMDD). PMDD affects some women in the days before their period. PMDD is different from premenstrual syndrome (PMS). The mood symptoms (anger, sadness, tension, etc) in PMDD are more severe than in PMS and affect the woman's daily activities and relationships with others. Sertraline Pfizer belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). They are thought to work by blocking the uptake of a chemical called serotonin into nerve cells in the brain. Serotonin and other chemicals called amines are involved in controlling mood. Your doctor, however, may prescribe Sertraline Pfizer for another purpose. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY SERTRALINE PFIZER HAS BEEN PRESCRIBED FOR YOU. Sertraline Pfizer should not be used in children and adolescents under the age of 18 years for the treatment of any medical condition other than obsessive compulsive disorder (OCD). The safety and efficacy of Sertraline Pfizer for the treatment of medical conditions (other than OCD) in this age group has not been satisfactorily established. For the treatment of OCD, Sertraline Pfizer is not recommended for use in children under the age of 6, Կարդացեք ամբողջական փաստաթուղթը
Version: pfpsertt10513 Supersedes: pfpsertt10413 Page 1 of 25 PRODUCT INFORMATION SERTRALINE PFIZER ® (SERTRALINE HYDROCHLORIDE) NAME OF THE MEDICINE SERTRALINE PFIZER Sertraline (as hydrochloride) 50 mg and 100 mg capsules. SERTRALINE PFIZER is an antidepressant for oral administration and contains the active ingredient sertraline hydrochloride. Sertraline hydrochloride is chemically unrelated to tricyclic, tetracyclic or other available antidepressant agents. The structural formula of sertraline hydrochloride is shown below: Chemical name: (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1- naphthalenamine hydrochloride Molecular formula: C 17 H 17 NCl 2 .HCl Molecular weight: 342.7 CAS Registry Number: 79559-97-0. DESCRIPTION Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol and sparingly soluble in ethanol. SERTRALINE PFIZER is supplied for oral administration as film coated tablets containing sertraline hydrochloride equivalent to 50 and 100 mg sertraline and the following inactive ingredients: cellulose – microcrystalline, calcium hydrogen phosphate, hydroxypropyl cellulose, sodium starch glycollate, magnesium stearate, white Opadry, clear Opadry. Version: pfpsertt10513 Supersedes: pfpsertt10413 Page 2 of 25 PHARMACOLOGY PHARMACODYNAMICS The mechanism of action of sertraline is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin (5HT). Studies at clinically relevant doses in man have demonstrated that sertraline blocks the uptake of serotonin into human platelets. _In vitro_ studies in animals also sugg Կարդացեք ամբողջական փաստաթուղթը