PREDNISONE tablet

Country: Ամերիկայի Միացյալ Նահանգներ

language: անգլերեն

source: NLM (National Library of Medicine)

active_ingredient:

PREDNISONE (UNII: VB0R961HZT) (PREDNISONE - UNII:VB0R961HZT)

MAH:

St Marys Medical Park Pharmacy

INN:

PREDNISONE

composition:

PREDNISONE 5 mg

prescription_type:

PRESCRIPTION DRUG

authorization_status:

Abbreviated New Drug Application

SPC

PREDNISONE- PREDNISONE TABLET
ST MARYS MEDICAL PARK PHARMACY
----------
PREDNISONE TABLETS, USP
1 MG, 2.5 MG, 5 MG, 10 MG AND 20 MG
RX ONLY
DESCRIPTION
PredniSONE Tablets contain prednisone which is a glucocorticoid.
Glucocorticoids are adrenocortical
steroids, both naturally occurring and synthetic, which are readily
absorbed from the gastrointestinal
tract. Prednisone is a white to practically white, odorless,
crystalline powder. It is very slightly soluble
in water; slightly soluble in alcohol, chloroform, dioxane, and
methanol.
The chemical name for prednisone is pregna-1,4-diene-3,11,20-trione
monohydrate,17,21-dihydroxy-.
The structural formula is represented below:
PredniSONE Tablets are available in 5 strengths: 1 mg, 2.5 mg, 5 mg,
10 mg and 20 mg.
_Inactive ingredients:_ 1 mg — lactose monohydrate, magnesium
stearate, microcrystalline cellulose,
pregelatinized starch, sodium starch glycolate, stearic acid; 2.5 mg
— lactose monohydrate, magnesium
stearate, microcrystalline cellulose, pregelatinized starch, sodium
starch glycolate, stearic acid; 5 mg—
colloidal silicon dioxide, lactose monohydrate, magnesium stearate,
pregelatinized starch, sodium
starch glycolate; 10 mg—colloidal silicon dioxide, lactose
monohydrate, magnesium stearate,
pregelatinized starch, sodium starch glycolate; 20 mg—FD&C Yellow #6
Lake, lactose monohydrate,
magnesium stearate, microcrystalline cellulose, sodium starch
glycolate.
CLINICAL PHARMACOLOGY
Naturally occurring glucocorticoids (hydrocortisone and cortisone),
which also have salt-retaining
properties, are used as replacement therapy in adrenocortical
deficiency states. Their synthetic analogs
are primarily used for their potent anti-inflammatory effects in
disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In
addition, they modify the body's
immune responses to diverse stimuli.
INDICATIONS AND USAGE
PredniSONE Tablets are indicated in the following conditions:
1. ENDOCRINE DISORDERS
Primary or secondary adrenocortical ins