Medizine Syrup 5mg5mL

Երկիր: Մալայզիա

Լեզու: անգլերեն

Աղբյուրը: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ակտիվ բաղադրիչ:

CETIRIZINE HYDROCHLORIDE

Հասանելի է:

World Medicare Supplies Sdn Bhd

INN (Միջազգային անվանումը):

CETIRIZINE HYDROCHLORIDE

Միավորները փաթեթում:

120 ml

Պատրաստված է:

SUNWARD PHARMACEUTICAL SDN. BHD.

Տեղեկատվական թերթիկ

MEDIZINE SYRUP 5MG/5ML
Cetirizine hydrochloride (5mg/5ml)
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1. What Medizine Syrup is used for
2. How Medizine Syrup works
3. Before you use Medizine Syrup
4. How to use Medizine Syrup
5. While you are using it
6. Side effects
7. Storage & disposal of Medizine Syrup
8. Product description
9. Manufacturer and Product Registration
Holder
10. Date of revision
WHAT MEDIZINE SYRUP IS USED FOR
Medizine Syrup is used to treat adults and
children aged 2 and over who have hay fever
(seasonal
allergic
rhinitis),
year
round
allergies
such
as
dust
or
pet
allergies
(perennial
allergic
rhinitis)
and
urticaria
(swelling, redness and itchiness of the skin).
HOW MEDIZINE SYRUP WORKS
The active ingredient this medicine is cetiriz-
ine. It belongs to a group of medicines called
antihistamines. It works by blocking a certain
natural substance (histamine) that your body
makes during an allergic reaction.
BEFORE YOU USE MEDIZINE SYRUP
_- When you must not use it _
Do not use Medizine Syrup if you:

are hypersensitive to cetirizine, hydroxyz-
ine,
piperazine
or
any
other
ingredients
listed at the end of the leaflet.

have severe kidney failure (creatinine clear-
ance less than 10ml/min).
_Children_
Medizine Syrup is not recommended to be use
for children under 2 years of age.
_ _
_- Before you start to use it _
Tell your doctor before taking this medicine if
you have:

moderate or severe kidney problem.

have difficulty in urination.

fits.

convulsion.
_Pregnancy and breastfeeding _
You should check with your doctor if you are
or think you may be pregnant, planning to
become pregnant or if you are breastfeeding.
It is not recommended for pregnant women and
nursing mothers unless the expected benefit
outweighs any potential risks.
There
is
inadequate
evidence
of
safety
in
human pregnancy or fertility. Safety during
pregnancy has not been established. Caution
should be taken when breastfeeding as cetiriz-
ine found excreted in breast milk.
_- Taki

Ապրանքի հատկությունները

Each 5ml contains :
Cetirizine HCl
5mg
PHARMACOLOGY:
In experimental animals, cetirizine has been shown to be an anti-H1
agent devoid of any significant anticholinergic or antiserotonin
effects. At pharmacological active doses, it induces neither sedation
nor behavioural changes. This may be explained by the fact that
cetirizine does not cross the blood-brain barrier. It was shown in
human pharmacology studies that cetirizine will inhibit certain
effects
produced by exogenous histamine. This activity appears rapidly.
Cetirizine also inhibits the effects produced by endogenous
histamine released in vivo by an agent eg 48/80. Finally, it inhibits
the cutaneous reaction induced by VIP (Vasoactive Intestinal
Polypeptide) and substance P, neuropeptides that are believed to take
part in the allergic reaction. Cetirizine markedly reduces
bronchial hyper-reactivity to histamine in the asthmatic patient. It
also reduces the allergic reaction induced by specific allergens.
These effects are obtained without central effects being demonstrated
either by psychometric test or by a quantified EEG.
PHARMACOKINETICS:
INDICATIONS:
SIDE EFFECTS / ADVERSE REACTIONS:
PRECAUTIONS/WARNINGS:
USE IN PREGNANCY & LACTATION:
MEDIZINE SYRUP
5MG/5ML
Adults and children of 2 years and above: symptomatic treatment of
seasonal allergic rhinitis, perennial allergic rhinitis and urticaria
of allergic origin.
Activities Requiring Mental Alertness: In clinical trials the
occurrence of somnolence has been reported in some patients taking
Cetirizine: due caution should therefore be exercised when driving a
car or operating potentially dangerous machinery.
Dosage adjustment is necessary in patients with moderate or severe
renal impairment (see section Recommended Dose). Caution
should be taken in patients with predisposition factors of urinary
retention (e.g. spinal cord lesion, prostatic hyperplasia) as
cetirizine
may increase the risk of urinary retention.Caution in epileptic
patients and patients at risk of convulsions is recommended. For
patients w