Country: Ամերիկայի Միացյալ Նահանգներ
language: անգլերեն
source: NLM (National Library of Medicine)
Erythromycin (UNII: 63937KV33D) (Erythromycin - UNII:63937KV33D)
Avera McKennan Hospital
Erythromycin
Erythromycin 250 mg
PRESCRIPTION DRUG
Abbreviated New Drug Application
ERYTHROMYCIN- ERYTHROMYCIN TABLET, FILM COATED AVERA MCKENNAN HOSPITAL ---------- ERYTHROMYCIN TABLETS, USP Film-coated Tablets RX ONLY To reduce the development of drug-resistant bacteria and maintain the effectiveness of Erythromycin Tablets and other antibacterial drugs, Erythromycin Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Erythromycin Tablets, USP are an antibacterial product containing erythromycin, USP, in a unique, nonenteric film coating for oral administration. Erythromycin Tablets are available in two strengths containing either 250 mg or 500 mg of erythromycin base. Erythromycin is produced by a strain of _Saccharopolyspora erythraea_ (formerly _Streptomyces erythraeus_) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids. Erythromycin is a white to off-white powder, slightly soluble in water, and soluble in alcohol, chloroform, and ether. Erythromycin is known chemically as (3R*, 4S*, 5S*, 6R*, 7R*, 9R*, 11R*, 12R*, 13S*, 14R*)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-??-L-_ribo_-hexopyranosyl)oxy]-14-ethyl- 7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-??-D-_xylo_ - hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione. The molecular formula is C H NO , and the molecular weight is 733.94. The structural formula is: INACTIVE INGREDIENTS Colloidal silicon dioxide, croscarmellose sodium, crospovidone, D&C Red No. 30 Aluminum Lake, hydroxypropyl cellulose, hypromellose, hydroxypropyl methylcellulose phthalate, magnesium stearate, microcrystalline cellulose, povidone, polyethylene glycol, propylene glycol, sodium citrate, sodium hydroxide, sorbic acid, sorbitan monooleate, talc, and titanium dioxide. CLINICAL PHARMACOLOGY 37 67 13 Orally administered erythromycin base and its salts are readily absorbed in the microbiologically active form. Interindividual variations in the absorption of erythromycin are, however, observed, and some patients read_full_document