Country: Մալայզիա
language: անգլերեն
source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MONENSIN SODIUM
ELANCO MALAYSIA SDN BHD
MONENSIN SODIUM
25.00 mcg/mL
Elanco Clinton Laboratories
Template: LA_8_5x12_5in_v3_1 50 mm Rule Bar NON PRINTING BLACK PMS 137 C LA_8_5x12_5in_v3_1 MX6520 5.5 pt DMc 21-Mar-2022 P1b ELANCO ARTWORK LEGEND v16 103370AP YL103370X AF1308 YL102466X Elancoban 200 Label 25kg POD label N/A GTIN Not Required ACQ_LOT 0123456789ABCDEFGHIJKLMNOPQRSTUVWXYZ ACQ_MFGDATE 0123456789/- ACQ_EXPDATE 0123456789/- YL103370X AF1308 ACQ_LOT 0123456789ABCDEFGHIJKLMNOPQRSTUVWXYZ ACQ_MFGDATE 0123456789/- ACQ_EXPDATE 0123456789/- _Granulated Premix 200 g/kg_ NET WEIGHT: 25 KG For Use in Chicken and Turkey Feeds Only Granular medicated premix for the preparation of medicated animal feed FOR ANIMAL USE ONLY KEEP OUT OF REACH OF CHILDREN JAUHI UBAT DARI KANAK -KANAK ACTIVE DRUG INGREDIENT: 200 g/kg of Monensin (as Monensin Sodium) PRESERVATIVE: N/A PRODUCT DESCRIPTION: It occurs as a dark brown, speckled with straw-colored particles, free-flowing granular meal consisting of monensin and diluents blended to a monensin activity of 200 g/kg (90.7 g/lb). Pharmacodynamics: Monensin is a member of the class of compounds known as monocarboxylic acid, polyether, ionophorous antibiotics. It has been determined that the ionophores form complexes with alkali metal cations, e.g. sodium, and, therefore, are capable of transporting these bound ions through biological membranes. In the intestinal lumen with ionophore activity present, coccidial sporozoites accumulate measurable quantities of the ionophore and the destructive process begins. Host-cell invasion is significantly inhibited by the ionophore activity against free coccidia in the intestinal lumen. Development of a sporozoite that successfully invades a host cell is inhibited, and the ionophore accumulated while the sporozoite was free in the intestinal lumen continues its destructive process. The ionophore activity selectively destroys intracellular sporozoites or trophozoites while remaining relatively non-injurious to the host cells. Pharmacokinetics: The pharmacokinetic profile of monensin was evaluated in broiler chickens following administration by read_full_document