DOPAMINE HCI - FRESENIUS 200 MG5 ML

Երկիր: Իսրայել

Լեզու: անգլերեն

Աղբյուրը: Ministry of Health

Ակտիվ բաղադրիչ:

DOPAMINE HYDROCHLORIDE

Հասանելի է:

MEDIC TRIM HEALTHCARE LTD

ATC կոդը:

C01CA04

Դեղագործական ձեւ:

SOLUTION FOR INFUSION

Կազմը:

DOPAMINE HYDROCHLORIDE 200 MG / 5 ML

Կառավարման երթուղին:

I.V

Ռեկվիզորի տեսակը:

Required

Պատրաստված է:

FRESENIUS KABI MANUFACTURING SA (PTY) LTD, SOUTH AFRICA

Թերապեւտիկ տարածք:

DOPAMINE

Թերապեւտիկ ցուցումներ:

To correct hemodynamic imbalances associated with myocardial infarction trauma septic shock and cardiac surgery. Dopamine Hydrochloride is used in the treatment of : 1. Shock unresponsive to replacement of fluid loss and especially where renal function is impaired. 2. To correct haemodynamic imbalances associated with myocardial infarction trauma septic shock and cardiac surgery. 3. It is also used in the management of chtonic refractory congestive heart failure.

Հաստատման ամսաթիվը:

2012-05-31

Ապրանքի հատկությունները

Dopamine HCl-Fresenius
200 mg/5 ml
1.
PROPRIETARY NAME
(and dosage form)
Dopamine HCl-Fresenius 200 mg/5 ml (Injection)
2.
COMPOSITION
200 mg/5 ml Dopamine hydrochloride with
0,1% w/v Potassium metabisulphite
3.
PHARMACOLOGICAL CLASSIFICATION
A 6.1 - Cardiac stimulants
4.
PHARMACOLOGICAL ACTION
Dopamine hydrochloride exerts a positive inotropic effect on the
myocardium, acting as an agonist at ß
1
adrenergic receptors.
In addition, it has the capacity to release norepinephrine from
nerve terminals, and this also contributes to its effects on the
heart.
Dopamine hydrochloride appears to increase systolic and pulse
pressure and has either no effect on or slightly increases diastolic
blood pressure. Total peripheral resistance is usually unchanged
when low or intermediate therapeutic doses are given.
This is probably due to the ability of dopamine hydrochloride to
reduce regional arterial resistance in the mesentery and the kidney,
while producing minor increases in other vascular beds.
The effect of dopamine hydrochloride on the renal vasculature
appears to be mediated by a specific dopaminergic receptor.
In relatively low doses, infusion of 2
μ
g/kg/minute dopamine
hydrochloride is associated with an increase in glomerular filtration
rate, renal blood flow, and sodium excretion (dopaminergic
mechanism).
5.
INDICATIONS
Dopamine hydrochloride is used in the treatment of:
1.
Shock unresponsive to replacement of fluid loss and especially
where renal function is impaired.
2.
To correct haemodynamic imbalances associated with
myocardial infarction, trauma, septic shock, and cardiac surgery.
3.
It is also used in the management of chronic refractory
congestive heart failure.
6.
CONTRA-INDICATIONS
The safety of dopamine hydrochloride in pregnancy and lactation
has not been established.
The safety and efficacy of dopamine hydrochloride in children has
not been established.
Dopamine hydrochloride should not be given to patients receiving
monoamine oxidase (MAO) inhibitors or within 14 days of
discontinuing such treatment.