Diamox 250mg tablets

Country: Միացյալ Թագավորություն

language: անգլերեն

source: MHRA (Medicines & Healthcare Products Regulatory Agency)

active_ingredient:

Acetazolamide

MAH:

Advanz Pharma

ATC_code:

S01EC01

INN:

Acetazolamide

dosage:

250mg

pharmaceutical_form:

Oral tablet

administration_route:

Oral

class:

No Controlled Drug Status

prescription_type:

Valid as a prescribable product

leaflet_short:

BNF: 11060000; GTIN: 5021691164739

PIL

PACKAGE LEAFLET: INFORMATION FOR THE USER
DIAMOX
® 250MG TABLETS
(acetazolamide)
IN THIS LEAFLET:
1.
What Diamox 250mg Tablets are and what they are used for
2.
Before you take Diamox 250mg Tablets
3.
How to take Diamox 250mg Tablets
4.
Possible side effects
5.
How to store Diamox 250mg Tablets
6.
Further information
Diamox
®
250mg Tablets (referred to as Diamox 250mg Tablets throughout this
leaflet) contain the active substance Acetazolamide. This belongs to a
group of medicines known as carbonic anhydrase inhibitors.
Diamox 250mg Tablets are used to treat:
• glaucoma (a condition of the eye), by reducing the pressure within
the eye
• abnormal retention of fluids (Diamox 250mg Tablets acts as a
diuretic)
• epilepsy (fits or convulsions).
DO NOT TAKE DIAMOX 250MG TABLETS IF:
• you know you are allergic to sulphonamides, sulphonamide
derivatives including acetazolamide or to any of the ingredients in
the medicine (listed in
Section 6 at the end of this leaflet)
• you have severe liver problems
• you have or have ever had severe kidney problems
• you have a particular type of glaucoma known as chronic non
congestive angle closure glaucoma (your doctor will be able to advise
you)
• you have reduced function of the adrenal glands – glands above
the kidneys – (also known as Addison’s disease)
• you have low blood levels of sodium and/or potassium or high blood
levels of chlorine (your doctor will advise you).
Speak to your doctor if any of the above applies to you.
TAKE SPECIAL CARE AND SPEAK TO YOUR DOCTOR BEFORE TAKING DIAMOX 250MG
TABLETS IF:
• you have or have ever had kidney problems such as kidney stones
• you have lung problems such as chronic bronchitis or emphysema,
which cause difficulty in breathing
• you are over the age of 65
• a small number of people being treated with anti-epileptics such
as Acetazolamide have had thoughts of harming or
killing themselves, if at any time you have these thoughts,
immediately contact your doctor.
Diamox 250mg Tablets may affect some medi

SPC

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
DIAMOX* 250mg Tablets
Acetazolamide Mercury_ _Pharma 250mg Tablets
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains 250mg acetazolamide BP.
Excipient(s) with known effect
For the full list of excipients, see section 6.1.
3
PHARMACEUTICAL FORM
Tablet.
White, circular shallow biconvex tablets with quarter breakline on one
side and
engraved “FW” and “147” on other side.
4.
CLINICAL PARTICULARS
4.1
THERAPEUTIC INDICATIONS
DIAMOX Tablets are for oral administration.
Acteazolamide is an enzyme inhibitor which acts specifically on
carbonic anhydrase.
It is indicated in the treatment of:
i)
_Glaucoma:_ DIAMOX Tablets is useful in glaucoma (chronic simple (open
angle)
glaucoma, secondary glaucoma, and perioperatively in acute angle
closure glaucoma
where delay of surgery is desired in order to lower intraocular
pressure) because it acts on
inflow, decreasing the amount of aqueous secretion.
ii)
_Abnormal retention of fluids:_ DIAMOX Tablets is a diuretic whose
effect is due to the
effect on the reversible hydration of carbon dioxide and dehydration
of carbonic acid
reaction in the kidney. The result is renal loss of HC0
3-
ion which carries out sodium,
water and potassium. DIAMOX Tablets can be used in conjunction with
other diuretics
when effects on several segments of the nepbron are desirable in the
treatment of fluid
retaining states.
iii)
_Epilepsy:_ In conjunction with other anticonvulsants best results
with DIAMOX Tablets
have been seen in petit mal in children. Good results, however, have
been seen in patients,
both children and adults, with other types of seizures such as grand
mal, mixed seizure
patterns, myoclonic jerk patterns etc.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
i)
Glaucoma (simple acute congestive and secondary):
Adults: 250 - 1,000mg (1-4 tablets) per 24 hours, usually in divided
doses for amounts
over 250mg daily.
ii)
Abnormal retention of fluid: Congestive heart failure, drug-induced
oedema.
Adults