Chemmart Citalopram

Երկիր: Ավստրալիա

Լեզու: անգլերեն

Աղբյուրը: Department of Health (Therapeutic Goods Administration)

Ակտիվ բաղադրիչ:

Citalopram hydrobromide

Հասանելի է:

Apotex Pty Ltd

Դաս:

Medicine Registered

Տեղեկատվական թերթիկ

CHEMMART CITALOPRAM

_Contains the active ingredient citalopram (as citalopram
hydrobromide)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about citalopram. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is
Chemmart Citalopram. It contains
the active ingredient citalopram (as
citalopram hydrobromide).
It is used to treat depression:
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Citalopram belongs to a group of
antidepressant medicines called
Selective Serotonin Reuptake
Inhibitors (SSRIs). Citalopram and
other SSRIs are thought to help by
increasing the amount of serotonin in
your brain.
Depression is longer lasting and/or
more severe than the 'low moods'
everyone has from time to time due
to the stress of everyday life. It is
thought to be caused by a chemical
imbalance in parts of the brain. This
imbalance affects your whole body
and can cause emotional and physical
symptoms such as feeling low in
spirit, loss of interest in activities,
b

Ապրանքի հատկությունները

Product Information – Australia 
Chemmart Citalopram Tablets 

Page 1 
CHEMMART CITALOPRAM TABLETS 

NAME OF THE MEDICINE 
Citalopram hydrobromide. 

Chemical Name:  
1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-
carbonitrile hydrobromide.  The active is present as a racemate. 

Structural Formula: 
.
HBr

Molecular Formula: 
C
20
H
21
FN
2
O.HBr 

Molecular Weight: 
405.3 

CAS Registry Number: 
59729-32-7 

DESCRIPTION 
Citalopram hydrobromide is a fine white to off-white, crystalline
material. 

Citalopram hydrobromide is sparingly soluble in water, soluble in ethanol (96%), freely soluble in 
chloroform and very slightly soluble in diethylether.  No
polymorphic forms have been detected. 

Each tablet contains 20 mg or 40 mg
of citalopram (as citalopram hydrobromide).  In addition, each 
tablet contains the
following inactive ingredients: lactose, cellulose-microcrystalline, croscarmellose 
sodium, magnesium stearate, titanium dioxide, macrogol 8000 and
hydroxyethylcellulose. 

PHARMACOLOGY 
PHARMACODYNAMICS 
Biochemical and behavioural studies have shown that citalopram is a potent inhibitor of serotonin (5-HT) 
uptake.  Tolerance to the inhibition of 5-HT uptake
is not induced by long-term treatment with citalopram. 

On the basis of _in vitro _studies, citalopram is one of the
most selective Serotonin Reuptake Inhibitors 
(SSRI) yet developed, with no, or minimal effect on
noradrenaline (NA), dopamine (DA) and gamma 
aminobutyric acid (GABA) uptake.  In comparison with other SSRls, the decreasing order of selectivity is 
escitalopram, citalopram, sertraline, paroxetine, fluvoxamine and
fluoxetine.  The clinical relevance of this 
_in vitro _finding has not been established. 

In contrast to many tricyclic antidepressants and some of the
newer SSRIs, citalopram