Երկիր: Ավստրալիա
Լեզու: անգլերեն
Աղբյուրը: Department of Health (Therapeutic Goods Administration)
amlodipine besilate,Atorvastatin calcium propylene glycol solvate
Apotex Pty Ltd
amlodipine besilate,Atorvastatin calcium propylene glycol solvate
CHEMMART AMLODIPINE / ATORVASTATIN _5/10, 5/20, 5/40, 5/80, 10/10, 10/20, 10/40 & 10/80 TABLETS_ _Contains the active ingredients amlodipine (as besylate) and atorvastatin (as calcium propylene glycol_ _solvate)_ CONSUMER MEDICINE INFORMATION _FOR A COPY OF A LARGE PRINT LEAFLET, PH: 1800 195 055_ WHAT IS IN THIS LEAFLET READ THIS LEAFLET CAREFULLY BEFORE TAKING YOUR MEDICINE. This leaflet answers some common questions about amlodipine and atorvastatin combination tablets. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. The information in this leaflet was last updated on the date listed on the last page. More recent information on this medicine may be available. ASK YOUR DOCTOR OR PHARMACIST: • if there is anything you do not understand in this leaflet, • if you are worried about taking your medicine, or • to obtain the most up-to-date information. You can also download the most up to date leaflet from www.apotex.com.au. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Pharmaceutical companies cannot give you medical advice or an individual diagnosis. Keep this leaflet with your medicine. You may want to read it again. WHAT THIS MEDICINE IS USED FOR The name of your medicine is Chemmart Amlodipine/Atorvastatin, Tablets. It contains the active ingredients amlodipine besylate and atorvastatin calcium propylene glycol solvate. It is used to: • treat high blood pressure • treat high cholesterol • treat angina (type of chest pain) • reduce the risk of heart attack or stroke in patients with high blood pressure who have coronary heart disease (CHD) or multiple risk factors for CHD. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason. This medicine is available only with a doctor's prescription. _HOW IT WORKS_ This medicine co Կարդացեք ամբողջական փաստաթուղթը
Product Information – Australia Chemmart AMLODIPINE/ATORVASTATIN Tablets Page 1 CHEMMART AMLODIPINE/ATORVASTATIN 5/10, 5/20, 5/40, 5/80, 10/10, 10/20, 10/40 & 10/80 TABLETS NAME OF THE MEDICINE Amlodipine (as besylate) and Atorvastatin (as calcium propylene glycol solvate) ACTIVE INGREDIENT #1 Amlodipine besylate Chemical Name: (3-ethyl 5-methyl (4_RS_)-2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulphonate) Structural Formula: Molecular Formula: C 20 H 25 CIN 2 O·C 6 H 5 SO 3 H. Molecular Weight: 567.05. CAS Registry Number: 111470-99-6. ACTIVE INGREDIENT #2 Atorvastatin (as calcium propylene glycol solvate) Chemical Name: calcium bis((3_R_,5_R_)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4- phenyl-1_H_-pyrrol-1-yl]-3,5-dihydroxyheptanoate)propylene glycol solvate Structural Formula: Molecular Formula: C 66 H 68 CaF 2 N 4 O 10 * C 3 H 8 O 2 . Molecular Weight: 1231.46. CAS Registry Number: 134523-03-8 (Atorvastatin calcium) Product Information – Australia Chemmart AMLODIPINE/ATORVASTATIN Tablets Page 2 DESCRIPTION Amlodipine besylate is a white or almost white powder that is slightly soluble in water and sparingly soluble in ethanol. Atorvastatin calcium propylene glycol solvate is a white to off-white crystalline powder that is sparingly soluble in methanol, practically insoluble in ethanol and very slightly soluble in acetonitrile. Amlodipine and atorvastatin combination tablets contains the following amount of amlodipine (as besylate) and atorvastatin (as calcium propylene glycol solvate) respectively: 5/10mg, 5/20mg, 5/40mg, 5/80mg, 10/10mg, 10/20mg, 10/40mg and 10/80mg. In addition, each tablet contains croscarmellose sodium, microcrystalline cellulose, iron oxide yellow, magnesium stearate, colloidal anhydrous silica, calcium acetate, OPADRY II complete film coating system 85F10919 Blue (ARTG #10379) (10mg/10mg, 10mg/20mg, 10mg/40mg and 10mg/80mg strengths only) and OPADRY II complete film coating system White 85F180001 (ARTG #108944) Կարդացեք ամբողջական փաստաթուղթը