B. BRAUN OSMOFUNDIN 20%

Երկիր: Մալայզիա

Լեզու: անգլերեն

Աղբյուրը: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ակտիվ բաղադրիչ:

Mannitol; SORBITOL

Հասանելի է:

B.BRAUN MEDICAL INDUSTRIES SDN BHD

INN (Միջազգային անվանումը):

Mannitol; SORBITOL

Միավորները փաթեթում:

250ml mL; 500 ml mL

Պատրաստված է:

B.BRAUN MEDICAL INDUSTRIES SDN BHD

Ապրանքի հատկությունները

COMPOSITION
Each 100 ml contains:
B. BRAUN
B. BRAUN
OSMOFUNDIN® 10%
OSMOFUNDIN® 20%
Mannitol
10.0 g
17.5 g
Sorbitol for Parenteral
Use
-
2.5 g
Sodium Chloride
0.26 g
-
Sodium
Acetate .3H
2
O
0.34 g
-
Water for Injections
to
100 ml
100 ml
Electrolytes:
mmol/l
Na
+
70
Cl
—
45
Acetate
—
25
Osmolarity:
690 mOsm/l
1100 mOsm/l
CHARACTERISTICS
B. Braun Osmofundin® contains mannitol, a hex-
avalent sugar alcohol which is not metabolised
but eliminated via the kidneys together with a
corresponding amount of water. Thus mannitol
promotes urine excretion by means of osmotic
diuresis and also improves renal blood flow. For
galenic reasons 2.5% sorbitol has been added to
B. Braun Osmofundin® 20%.
INDICATIONS
Prophylaxis of acute renal failure
Postoperative oliguria
In forced diuresis for eliminating toxic substanc-
es via the kidneys
For decreasing intracranial pressure in case of
cerebral oedema
Prior to cataract operations
Therapy-resistant oedema
For the B. Braun Osmofundin® test to determine
renal function
B. BRAUN OSMOFUNDIN® TEST:
100 ml of B. Braun Osmofundin® 20% or 200 ml
of B. Braun Osmofundin® 10% are infused within
15 minutes. If the urine excretion, which can be
accurately measured with the urimeter Ureofix®,
remains below 30-40 ml/h, then this may be in-
dicative of an organic renal damage. If, on the
contrary, the urine excretion exceeds 40 ml/h,
then the osmotherapy with B. Braun Osmofun-
din® can be continued, whereby a diuresis rate
of 100 ml/h should be finally aimed at.
DOSAGE
Unless otherwise prescribed:
B. Braun Osmofundin® 10%
500-1000 ml per day corresponding to 50-100 g
mannitol
B. Braun Osmofundin® 20%
250-500 ml per day corresponding to 50-100 g
of polyols (= mannitol + sorbitol)
Drop rate: 30-60 drops/min.  90-180 ml/h
The above total dose of 100 g mannitol in 24
hours should only be exceeded if at least 100
ml/h of urine are excreted.
ROUTE OF ADMINISTRATION I.V.
SIDE EFFECTS
Osmotherapy may involve enhanced renal fluid
and electrolyte losses accompanied by circula-
tory disturb