Երկիր: Մալայզիա
Լեզու: անգլերեն
Աղբյուրը: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
LOSARTAN POTASSIUM; HYDROCHLOROTHIAZIDE
Duopharma Marketing Sdn. Bhd.
LOSARTAN POTASSIUM; HYDROCHLOROTHIAZIDE
30tablet Tablets
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ ACETAN HCT ® Losartan potassium and Hydrochlorothiazide (50/12.5 mg, 100/25 mg) WHAT IS IN THIS LEAFLET 1. What Acetan HCT is used for 2. How Acetan HCT works 3. Before you use Acetan HCT 4. How to use Acetan HCT 5. While you are using it 6. Side effects 7. Storage and Disposal of Acetan HCT 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT ACETAN HCT IS USED FOR Acetan HCT lower high blood pressure, which doctors call hypertension. It may be used alone or in combination with other medicines. Ask your doctor if you have any questions about why Acetan HCT has been prescribed for you. Your doctor may have prescribed it for another purpose. HOW ACETAN HCT WORKS Acetan HCT contains two active ingredients, losartan potassium and hydrochlorothiazide. Losartan potassium belongs to a group of medicines called angiotensin II receptor antagonists. It helps lower high blood pressure by relaxing your blood vessels. Hydrochlorothiazide is a fluid tablet or diuretic. It helps lower high blood pressure by reducing the amount of fluid in the body by making your kidneys pass more water and salt. BEFORE YOU USE ACETAN HCT - _When you must not use it _ Do not take Acetan HCT if you have ever had an allergic reaction to: • Acetan HCT or Acetan • any of the ingredients listed at the end of this leaflet. • any sulfonamide or sulfur medicines (antibiotics or tablets to treat diabetes) Symptoms of an allergic reaction may include skin rash, hives, fever, swelling of the face, lips, mouth, throat or tongue which may cause difficulty breathing or swallowing. Do not take Acetan HCT if you are not passing urine. Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. Do not take this medicine to treat any other complaints unless your doctor has instructed you to do so. Do not give this medicine Կարդացեք ամբողջական փաստաթուղթը
(losartan potassium and hydrochlorothiazide) ACETAN HCT TABLET 50/12.5MG &100/25MG I. DESCRIPTION AND COMPOSITION Acetan HCT Tablet 50/12.5mg An ellipse, yellow film coated tablet with “ACE” on one side and ‘50’ on other side. Each tablet contains Losartan Potassium…………. 50.0 mg Hydrochlorothiazide…………...12.5 mg Acetan HCT Tablet 100/25mg An ellipse, light yellow colour film coated tablet with ‘ACE’ on one side and scored on other side. Each tablet contains Losartan Potassium…………. 100 mg Hydrochlorothiazide…………....25 mg II. THERAPEUTIC CLASS ACETAN HCT(losartan potassium and hydrochlorothiazide) is the combination of an angiotensin II receptor (type AT 1 ) antagonist and a diuretic. III. INDICATIONS HYPERTENSION ACETAN HCT is indicated for the treatment of hypertension, for patients in whom combination therapy is appropriate. HYPERTENSIVE PATIENTS WITH LEFT VENTRICULAR HYPERTROPHY ACETAN HCT is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hyperthrophy, but there is evidence that this benefit does not apply to BLACK patients.(See PRECAUTIONS, Race, CLINICAL PHARMACOLOGY, _Pharmacodynamics and _ _Clinical Effects, Losartan Potassium, Reduction in the Risk of Stroke, Race_ and DOSAGE AND ADMINISTRATION.) IV. CLINICAL PHARMACOLOGY MECHANISM OF ACTION Losartan-Hydrochlorothiazide The components of ACETAN HCT have been shown to have an additive effect on blood pressure reduction, reducing blood pressure to a greater degree than either component alone. This effect is thought to be a result of the complimentary actions of both components. Further, as a result of its diuretic effect, hydrochlorothiazide increases plasma renin activity, increases aldosterone secretion, decreases serum potassium, and increases the levels of angiotensin II. Administration of losartan blocks all the physiologically relevant actions of angiotensin II and through inhibition of aldosterone could tend to attenuate the potassium loss associated with the diuret Կարդացեք ամբողջական փաստաթուղթը