Ország: Kanada
Nyelv: angol
Forrás: Health Canada
VANCOMYCIN (VANCOMYCIN HYDROCHLORIDE)
GENERIC MEDICAL PARTNERS INC
J01XA01
VANCOMYCIN
500MG
POWDER FOR SOLUTION
VANCOMYCIN (VANCOMYCIN HYDROCHLORIDE) 500MG
INTRAVENOUS
10X10ML
Prescription
GLYCOPEPTIDES
Active ingredient group (AIG) number: 0131315003; AHFS:
APPROVED
2014-12-18
PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION PR VANCOMYCIN HYDROCHLORIDE FOR INJECTION USP 500 mg and 1 g of Vancomycin (as Vancomycin Hydrochloride) per vial Sterile Lyophilized Powder for Solution ANTIBIOTIC Generic Medical Partners Inc. Date of Revision: 1500 Don Mills Road, Suite 406 October 26, 2020 Toronto, ON M3B 3K4 Control No.: 239577 2 PR VANCOMYCIN HYDROCHLORIDE FOR INJECTION USP ANTIBIOTIC ACTIONS The inhibition of cell wall synthesis has been shown by _ in vitro _studies to be responsible for the bactericidal action of vancomycin against many gram-positive bacteria. There is also evidence that RNA synthesis is selectively inhibited and the permeability of the cell membrane is altered by vancomycin. INDICATIONS AND CLINICAL USE Vancomycin Hydrochloride for Injection USP is indicated in the therapy of severe or life- threatening staphylococcal infections in patients who cannot receive or have failed to respond to the penicillins or cephalosporins, or who have infections with staphylococci resistant to other antibiotics, including methicillin. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Vancomycin Hydrochloride for Injection USP and other antibacterial drugs, Vancomycin Hydrochloride for Injection USP should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. In the treatment of staphylococcal endocarditis, vancomycin has been used successfully alone. In other infections due to staphylococci, including osteomyelitis, pneumonia, septicemia and soft- tissue infections, vancomycin's effectiveness has been documented. Antibiotics are used as adjuncts to appropriate surgical measures when staphylococcal infections are localized and purulen Olvassa el a teljes dokumentumot