Ország: Egyesült Államok
Nyelv: angol
Forrás: NLM (National Library of Medicine)
oxytetracycline hydrochloride (UNII: 4U7K4N52ZM) (oxytetracycline - UNII:X20I9EN955), hydrocortisone acetate (UNII: 3X7931PO74) (hydrocortisone - UNII:WI4X0X7BPJ)
Roerig
oxytetracycline hydrochloride and hydrocortisone acetate
SUSPENSION
OPHTHALMIC
PRESCRIPTION DRUG
For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists. Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical radiation, thermal burns, or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye. The particular anti-infective drug in this product is active against the following common bacterial eye pathogens: - Staphylococcus aureus - Streptococci , including Streptococcus pneumoniae - Escherichia
Terra-Cortril Ophthalmic Suspension (NDC 0049-0670-48) is supplied in 5 ml vials with separate sterile dropper.
TERRA-CORTRIL- OXYTETRACYCLINE HYDROCHLORIDE AND HYDROCORTISONE ACETATE SUSPENSION ROERIG ---------- TERRA-CORTRIL® TERRAMYCIN® (OXYTETRACYCLINE HCL) —CORTRIL® (HYDROCORTISONE ACETATE) OPHTHALMIC SUSPENSION DESCRIPTION Terra-Cortril suspension combines the antibiotic, oxytetracycline HCl (C H N O •HCl) and the adrenocorticoid, hydrocortisone acetate (C H O ). EACH ML OF TERRA-CORTRIL CONTAINS TERRAMYCIN (OXYTETRACYCLINE HCL) EQUIVALENT TO 5 MG OF OXYTETRACYCLINE, AND 15 MG OF CORTRIL (HYDROCORTISONE ACETATE) INCORPORATED IN MINERAL OIL WITH ALUMINUM TRISTEARATE. _FOR OPHTHALMIC USE ONLY._ CLINICAL PHARMACOLOGY Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticoids may inhibit the body's defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case. The anti-infective component in the combination is included to provide action against specific organisms susceptible to it. Terramycin is considered active against the following microorganisms: Rickettsiae (Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox and tick fevers), _Mycoplasma pneumoniae_ (PPLO, Eaton Agent), Agents of psittacosis and ornithosis, Agents of lymphogranuloma venereum and granuloma inguinale, The spirochetal agent of relapsing fever _(Borrelia recurrentis)_. The following gram-negative microorganisms: _Haemophilus ducreyi_ (chancroid), _Pasteurella pestis_ and _Pasteurella tularensis_, _Bartonella bacilliformis,_ _Bacteroides_ species, _Vibrio comma_ and _Vibrio fetus_, _Brucella_ species (in conjunction with streptomycin). Because many strains of the following groups of microorganisms have been shown to be resistant to tetracyclines, culture and susceptibility testing are recommended. Oxytetracycline is indicated for treatment of infections caused by the following gram-negative microorganisms, when bacteriologic testing in Olvassa el a teljes dokumentumot