Tenormin

Ország: Ausztrália

Nyelv: angol

Forrás: Department of Health (Therapeutic Goods Administration)

Aktív összetevők:

Atenolol

Betegtájékoztató

TENORMIN(R)
1
TENORMIN(R)
_Atenolol_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about TENORMIN. It
does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have benefits and
risks.  Your doctor has weighed the
risks of you taking TENORMIN
against the benefits they expect it
will have for you.
This medicine may also be used in
emergency situations where you may
be unconscious. In this case, this
leaflet may be given to you after the
medicine has been used.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT TENORMIN IS
USED FOR
TENORMIN belongs to a group of
medicines called beta-blockers.
It works by affecting the body's
response to certain nerve impulses,
especially in the heart. As a result, it
decreases the heart's need for blood
and oxygen and therefore reduces the
amount of work the heart has to do.
It widens the blood vessels in the
body, causing  blood pressure to fall.
It also helps the heart to beat more
regularly.
TENORMIN is used to:
*
lower high blood pressure, which
is called hypertension
*
prevent angina
*
treat irregular heart rhythm or
beat called arrhythmias
*
treat heart attacks, or reduce your
risk of heart complications
following a heart attack
TENORMIN may be either used
alone or in combination with other
medicines to treat your condition.
TENORMIN may also be used in
emergency situations or during
surgery to treat a fast heart beat
before, during or after surgery.
_HYPERTENSION:_
All people have blood pressure. This
pressure helps to push blood all
around your body. Your blood
pressure changes during the day,
depending on how busy you are or
how you are feeling.
You have hypertension (high blood
pressure) when your blo

Termékjellemzők

Tenormin Product Information 
CV.000-393-003.2.0 
TENORMIN
®

PRODUCT INFORMATION 
NAME OF THE DRUG 
Atenolol is 2-[4-(2-hydroxy-3-isopropylaminopropoxy) phenyl]
acetamide 
DESCRIPTION 
_Atenolol_: 
Beta-adrenoreceptor blocking agent structurally related to
propranolol and differing 
from it by substitution on the aromatic ring. 
TENORMIN tablets: contain 50 mg of the active ingredient atenolol.
 The tablets 
also contain magnesium carbonate - heavy, starch - maize, sodium
lauryl sulfate, 
gelatin and magnesium stearate. 
PHARMACOLOGY 
TENORMIN is a beta-adrenoreceptor blocking drug which acts
preferentially on 
beta-receptors in the heart.  Selectivity decreases with increasing
dose.  It has 
little intrinsic sympathomimetic activity and no membrane
stabilising activity.  
Atenolol is a racemic mixture and its activity resides in the S(-)
enantiomer.  It 
reduces raised blood pressure by an unknown mechanism and also
inhibits 
exercise induced tachycardia and decreases plasma renin
concentration.  It 
causes slight airways obstruction but less than that seen with
nonselective 
beta-blockers.  The inhibition of exercise induced tachycardia is
correlated with 
blood levels but there is no correlation between plasma concentrations
and 
antihypertensive effect.  TENORMIN is effective and well tolerated in
most ethnic 
populations although the response may be less in Afro-Caribbean black
patients. 
The possible mechanism of the anti-anginal activity of TENORMIN
appears to be 
due to a reduction in left ventricular work and oxygen utilisation
resulting (mainly) 
from the decrease in heart rate and contractility. 
The anti-arrhythmic effect of TENORMIN is apparently due to its
anti-sympathetic 
effect.  There is no evidence that membrane stabilising activity or
intrinsic 
sympathomimetic activity are necessary for anti-arrhythmic efficacy.
 By its 
anti-sympathetic effect, TENORMIN depresses sinus node function, 
atrioventricular node function and prolongs a