SOFRAMYCIN SKIN OINTMENT

Ország: Kanada

Nyelv: angol

Forrás: Health Canada

Aktív összetevők:

FRAMYCETIN SULFATE; GRAMICIDIN

Beszerezhető a:

SEARCHLIGHT PHARMA INC

ATC-kód:

D06AX30

INN (nemzetközi neve):

COMBINATIONS OF ANTIBIOTICS

Adagolás:

15MG; 50MCG

Gyógyszerészeti forma:

OINTMENT

Összetétel:

FRAMYCETIN SULFATE 15MG; GRAMICIDIN 50MCG

Az alkalmazás módja:

TOPICAL

db csomag:

250ML

Recept típusa:

Prescription

Terápiás terület:

ANTIBIOTICS

Termék összefoglaló:

Active ingredient group (AIG) number: 0205699001; AHFS:

Engedélyezési státusz:

APPROVED

Engedély dátuma:

2000-11-03

Termékjellemzők

PRESCRIBING INFORMATION
PR SOFRAMYCIN ® NASAL SPRAY
Framycetin sulfate, gramicidin and phenylephrine hydrochloride nasal
spray
Antibiotic-Decongestant
PR SOFRAMYCIN ® SKIN OINTMENT
Framycetin sulfate and gramicidin ointment
Antibiotic
PR SOFRAMYCIN ® STERILE EYE OINTMENT
Framycetin sulfate ophthalmic ointment
Antibiotic
Pr SOFRAMYCIN ® EYE DROPS
Framycetin sulfate eye drops
Antibiotic
Searchlight Pharma Inc.
1600 Notre-Dame West, Suite 312
Montreal, QC
H3J 1M1
Date of Preparation:
FEB 08, 2023
Submission Control No: 270992
PHARMACOLOGY
Framycetin, a broad spectrum aminoglycoside antibiotic, is usually
bactericidal in action.
Although the exact mechanism of action has not been fully elucidated,
the drug appears
to inhibit protein synthesis in susceptible bacteria by binding to
ribosomal subunits. In
general, framycetin is active against many aerobic gram-negative
bacteria and some
aerobic gram-positive bacteria
Gramicidin is a cyclic polypeptide antibiotic. It alters the cation
content of the bacterial
cell wall. Gramicidin is primarily effective against gram-positive
organisms.
Phenylephrine is a sympathomimetic amine which acts predominantly on
alpha-
adrenergic receptors. Topical application to the nasal mucosa results
in the constriction
of dilated arterioles and a reduction in nasal congestion. In
addition, nasal secretions are
reduced, and drainage of sinus secretion is increased. Nasal
ventilation and aeration are
improved temporarily.
INDICATIONS AND CLINICAL USE
_Nasal Spray : _For use in the local treatment of infections and/or
congestion caused by
susceptible
organisms
in
acute
rhino-sinusitis,
crusting
rhinitis,
nasal
conditions
accompanying the common cold and for post-operative care of patients
who have
undergone intranasal or sinus surgery.
Prophylactic use, for reduction of nasal carriage of staphylococci.
_Skin Ointment: _For local use in the treatment of infections caused
by pyogenic organisms,
in particular S. aureus, the proteus group of bacteria, coliforms and
P. aeruginosa. The
treatment