ROSULA sodium sulfacetamide 10% and sulfur 5% cloth

Ország: Egyesült Államok

Nyelv: angol

Forrás: NLM (National Library of Medicine)

Aktív összetevők:

SULFACETAMIDE SODIUM (UNII: 4NRT660KJQ) (SULFACETAMIDE - UNII:4965G3J0F5)

Beszerezhető a:

Avion Pharmaceuticals, LLC

INN (nemzetközi neve):

SULFACETAMIDE SODIUM

Összetétel:

SULFACETAMIDE SODIUM 100 mg in 1 g

Recept típusa:

PRESCRIPTION DRUG

Engedélyezési státusz:

unapproved drug other

Termékjellemzők

ROSULA- SODIUM SULFACETAMIDE 10% AND SULFUR 5% CLOTH
AVION PHARMACEUTICALS, LLC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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ROSULA
(SODIUM SULFACETAMIDE 10% AND SULFUR 5%)
CLEANSING CLOTHS
RX ONLY
DESCRIPTION
Sodium sulfacetamide is a sulfonamide with antibacterial activity
while sulfur acts as a keratolytic
agent. Chemically sodium sulfacetamide is N-[(4-aminophenyl)
sulfonyl]-acetamide, monosodium salt,
monohydrate. The structural formula is:
Each cloth of Rosula™ Cleansing Cloths is coated with a
cleanser-based formulation. Each gram of
this cleanser-based formulation contains 100 mg of Sodium
Sulfacetamide and 50 mg of Sulfur. The
cleanser base consists of: Butylated hydroxytoluene, Disodium EDTA,
Disodium laureth
sulfosuccinate and Disodium lauryl sulfoacetate, Emulsifying wax,
Hydrochloric acid, Methyl paraben,
Mineral oil, PPG-hydroxyethyl coco isostearamide, Propyl paraben,
Purified water, Sodium cocoyl
isethionate and Sodium thiosulfate.
CLINICAL PHARMACOLOGY
The most widely accepted mechanism of action of sulfonamides is the
Woods-Fildes theory, which is
based on the fact that sulfonamides act as competitive antagonists to
para-aminobenzoic acid (PABA), an
essential component for bacterial growth. While absorption through
intact skin has not been determined,
sodium sulfacetamide is readily absorbed from the gastrointestinal
tract when taken orally and excreted
in the urine, largely unchanged. The biological half-life has
variously been reported as 7 to 12.8 hours.
The exact mode of action of sulfur in the treatment of acne is not
known, but it has been reported that it
inhibits the growth of Propionibacterium acnes and the formation of
free fatty acids.
INDICATIONS
Rosula™ Cleansing Cloths are indicated in the topical control of
acne vulgaris, acne rosacea and
seborrheic dermatitis.
CONTRAINDICATIONS
Rosula™ Cleansing Cloths are contraindicated fo