Ország: Malajzia
Nyelv: angol
Forrás: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
ASPIRIN; GLYCINE
APEX PHARMACY MARKETING SDN. BHD.
ASPIRIN; GLYCINE
3 x 10 Tablets
XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ ________________________________________________________________________________________________________ _________________________________________________________________________________________________________ 1 WHAT IS IN THIS LEAFLET 1. What Recadin is used for 2. How Recadin works 3. Before you use Recadin 4. How to use Recadin 5. While you are using it 6. Side effects 7. Storage and Disposal of Recadin 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT RECADIN IS USED FOR Recadin is used as a platelet aggregation inhibitor in patients following aortocoronary by-pass surgery, to prevent graft occlusion. Conditions where modification of platelet behavior is considered beneficial, including transient ischaemic attacks, secondary prevention of myocardial infarction and for prophylaxis against stroke, vascular occlusion and deep vein thrombosis. HOW RECADIN WORKS Aspirin reduces the stickiness of platelets, where formation of clot is less likely to be occurred in the blood vessels. Glycine helps to reduce gastric irritation caused by aspirin. BEFORE YOU USE RECADIN _- When you must not to use it _ Do not use Recadin if you are known hypersensitivity to any ingredients in this medicine. _ _ _Pregnancy and lactation _ • Do not take Recadin if you are pregnant, trying to get pregnant or think you may be pregnant. • Do not take Recadin _ _ if you are breast- feeding. Ask your doctor or pharmacist for advice before taking any medicine. _ _ _- Before you start to use it _ Tell your doctor or pharmacist if: • You are pregnant or plan to get pregnant. _ _ • You are breast-feeding. _ _ _ _ _- Taking other medicines _ Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. HOW TO USE RECADIN _- How much to use_ For oral use only. Gastric irritation may be reduced by taking doses after food. _Adults_ : Take one tablet dail Olvassa el a teljes dokumentumot
Important Information. Please read carefully. RECADIN TABLET WHAT IS RECADIN? Description, Dosage form and Packaging RECADIN is a white to off-white, round, normal convex tablet, plain on both sides. Each tablet contains Aspirin 100mg and Glycine 45mg. Available in pack size of 30 tablets per box (10 tablets per blister, and 3 blisters in a box). WHAT IS RECADIN USED FOR? Recadin is used as a platelet aggregation inhibitor in patients following aortocoronary by-pass surgery, to prevent graft occlusion. Conditions where modification of platelet behavior is considered beneficial, including transient ischaemic attacks, secondary prevention of myocardial infarction and for prophylaxis against stroke, vascular occlusion and deep vein thrombosis. HOW RECADIN WORKS? RECADIN contains aspirin and glycine. Aspirin reduces the stickiness of platelets, where formation of clot is less likely to be occurred in the blood vessels. Glycine helps to reduce gastric irritation caused by aspirin. Pharmacodynamics Aspirin is a salicylate NSAID which inhibits platelet aggregation, in addition to its analgesic, anti-inflammatory, and antipyretic properties. Glycine is a non-essential aliphatic amino acids. It is used in the aspirin preparation as to reduce gastric irritation. Pharmacokinetics Aspirin is absorbed rapidly from the gastrointestinal tract when taken orally. Once absorbed, aspirin is rapidly converted to salicylate, but during the first 20 minutes after an oral dose aspirin is the main form of the drug in the plasma. Aspirin is 80 to 90% bound to plasma proteins and is widely distributed; its volume of distribution is reported to be 170 mL/kg in adults. Both aspirin and salicylate have pharmacological activity although only aspirin has an anti-platelet effect. Salicylate is extensively bound to plasma proteins and is rapidly distributed to all body parts. Salicylate is mainly eliminated by hepatic metabolism; the metabolites include salicyluric acid, salicyl phenolic glucuronide, salicylic acyl glucuronide, gentisic acid, an Olvassa el a teljes dokumentumot