POTASSIUM ACETATE injection, solution, concentrate

Ország: Egyesült Államok

Nyelv: angol

Forrás: NLM (National Library of Medicine)

Aktív összetevők:

POTASSIUM ACETATE (UNII: M911911U02) (POTASSIUM CATION - UNII:295O53K152)

Beszerezhető a:

Hospira, Inc.

Az alkalmazás módja:

INTRAVENOUS

Recept típusa:

PRESCRIPTION DRUG

Terápiás javallatok:

Potassium Acetate Injection, USP (2 mEq/mL) is indicated as a source of potassium, for the addition to large volume intravenous fluids, to prevent or correct hypokalemia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Potassium administration is contraindicated in patients with severe renal insufficiency or adrenal insufficiency and in diseases where high potassium levels may be encountered.

Termék összefoglaló:

Potassium Acetate Injection, USP is a Pharmacy Bulk Package which provides multiple single doses for continuous admixture compounding procedures is supplied as follows: Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Distributed by Hospira, Inc., Lake Forest, IL 60045 USA LAB-0903-2.0 9/2017

Engedélyezési státusz:

New Drug Application

Termékjellemzők

POTASSIUM ACETATE- POTASSIUM ACETATE INJECTION, SOLUTION, CONCENTRATE
HOSPIRA, INC.
----------
POTASSIUM ACETATE
INJECTION, USP
100 MEQ/50 ML
(2 MEQ/ML)
(2 MEQ K /ML AND 2 MEQ CH COO /ML)
PHARMACY BULK PACKAGE –
NOT FOR DIRECT INFUSION.
CONCENTRATED SOLUTION –
FOR INTRAVENOUS USE ONLY AFTER
DILUTION AND THOROUGH MIXING.
GLASS FLIPTOP VIAL
Rx only
DESCRIPTION
Potassium Acetate Injection, USP (2 mEq/mL) is a sterile,
nonpyrogenic, _concentrated solution_ of
potassium acetate in water for injection. The solution is administered
after dilution by the intravenous
route as an electrolyte replenisher. _It must not be administered
undiluted._
Each mL contains 196 mg of potassium acetate which provides 2 mEq each
of potassium (K ) and
acetate (CH COO ). The solution may contain acetic acid for pH
adjustment. The pH is 6.2 (range: 5.5 to
8.0). The osmolar concentration is 4 mOsmol/mL (calc.); specific
gravity is 1.089.
The Pharmacy Bulk Package is a sterile dosage which contains multiple
single doses for use only in a
pharmacy bulk admixture program.
The solution is intended as an alternative to potassium chloride to
provide potassium ion (K ) for
addition to large volume infusion fluids for intravenous use.
Potassium Acetate, USP is chemically designated CH COOK, and is
comprised of colorless crystals or
a white crystalline powder that is very soluble in water.
The Pharmacy Bulk Package is designed for use with manual, gravity
flow operations and automated
compounding devices for preparing sterile parenteral nutrient
admixtures. The Pharmacy Bulk Package
contains no bacteriostat, antimicrobial agent, or added buffer.
Multiple single doses may be dispensed
during continual aliquoting operations.
CLINICAL PHARMACOLOGY
As the principal cation of the intracellular fluid, potassium plays an
important role in fluid and
electrolyte balance. The normal potassium concentration in the
intracellular fluid compartment is about
160 mEq/liter. The normal serum potassium range is 3.5 to 5.0
mEq/liter. The kidney normally regulates
+