MENTOPIN ACETYLCYSTEINE 200 EFFERVESCENT TABLET

Ország: Malajzia

Nyelv: angol

Forrás: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktív összetevők:

Acetylcysteine

Beszerezhető a:

Medicell Pharmaceutical(malaysia) Sdn.bhd

INN (nemzetközi neve):

Acetylcysteine

db csomag:

10 x 2's tablet Tablets; 5 x 2's tablet Tablets

Gyártó:

Hermes Arzneimittel GmbH

Betegtájékoztató

_Consumer Medication Information Leaflet (RiMUP)_
1
MENTOPIN EFFERVESCENT TABLET
Acetylcysteine (200mg, 600mg)
WHAT IS IN THIS LEAFLET
1.
What Mentopin is used for
2.
How Mentopin works
3.
Before you use Mentopin
4.
How to use Mentopin
5.
While you are using
Mentopin
6.
Side effects
7.
Storage & disposal of
Mentopin
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT MENTOPIN IS USED FOR
Mentopin is used for
problems with the breathing
passages (respiratory tract).
These problems happen when too
much mucus being produced or
the mucus is too sticky.
HOW MENTOPIN WORKS
Mentopin works by making
mucus (phlegm) less sticky. This
makes the mucus easier to cough
out.
BEFORE YOU USE MENTOPIN
-
_When you must not use it _
_ _
Do not take Mentopin tablets if
you are:

allergic (hypersensitive) to
acetylcysteine or any of the
other ingredients of Mentopin
tablet _(see ingredient list) _
If you have these conditions, do
not take this medicine and inform
your doctor._ _
-
_Before you start to use it _
Inform your doctor if you have
any of the following conditions: _ _

asthma

gastric ulcer
_ _
_ _
-
_Taking other medicines _
You should always tell your doctor
if you are taking or have recently
taken any other medicines
including those obtained without a
prescription.
HOW TO USE MENTOPIN
-
_How much to use _
_ _
Adult dose:

200mg three times a day
OR

600mg daily as a single dose
-
_When to use it _
_ _
It is important that you take
Mentopin exactly as your doctor
has instructed.
Dissolve content of an
effervescent tablet in a glass of
water and drink immediately.
-
_How long to use it _
_ _
Take Mentopin tablets for the
duration of time your doctor
recommends.
-
_If you forget to use it _
_ _
If you miss a dose, do not try to
make up for it by doubling up on
the next dose. Just take the next
dose at the usual time. Consult
your doctor or pharmacist if you
have any doubts.
_- If you use too much (overdose) _
_ _
If you accidentally take an
overdose of Mentopin, cont

Termékjellemzők

PACKAGE INSERT
BRAND OR PRODUCT NAME
Mentopin Acetylcysteine 200mg
Effervescent Tablet
Mentopin Acetylcysteine 600mg
Effervescent Tablet
NAME AND STRENGTH OF ACTIVE
SUBSTANCE(S)
Mentopin Acetylcysteine 200mg
Effervescent Tablet contains 200mg
acetylcysteine.
Mentopin Acetylcysteine 600mg
Effervescent Tablet contains 600mg
acetylcysteine.
PRODUCT DESCRIPTION
Mentopin
Acetylcysteine
200mg
Effer-
vescent Tablet:
Round, white tablet with a smooth and
faultless surface.
Mentopin
Acetylcysteine
600mg
Effer-
vescent Tablet:
Round, white tablets with a smooth and
faultless surface and a break-mark on one
side.
PHARMACODYNAMICS
Acetylcysteine exerts its mucolytic action
through its free sulfhydryl group, which
opens the disulfide bonds and lowers mucus
viscosity.
This
action
increases
with
increasing pH and is most significant at pH 7
to 9. The mucolytic action of acetylcysteine
is not affected by the presence of DNA.
N-acetylcysteine has been demonstrated to
cause a decrease in sputum consistency, to
facilitate
easier
expectoration,
and
to
increase sputum volume. Bronchial mucus is
composed of over 95% water; however, the
physical characteristics of the mucus are due
to glycoproteins. These glycoproteins bind to
each other by way of disulfide bonds and
give the mucus viscosity. N-acetylcysteine
ruptures
these
disulfide
bonds
causing
depolymerization and a rapid decrease in
mucus viscosity. It also produces an irritative
bronchorrheic
effect
on
the
mucosa,
stimulatingmucociliary
clearance;
this
irritative effect may cause bronchospasm,
thus acetylcysteine is notrecommended in
asthmatics.
PHARMACOKINETICS
Absorption
Absorption
of
acetylcysteine
is
rapid
following
oral
administration,
but
the
bioavailability is only 6-10% due to extensive
first past metabolism.
Oral bioavailability is similar for a single 600-
mg dose and three 200-mg doses.
Peak plasma levels of acetylcysteine occur
approximately
one
hour
following
oraladministration.
Distribution
Acetylcysteine may be present in plasma as
the parent compound or as various