Ország: Ausztrália
Nyelv: angol
Forrás: Department of Health (Therapeutic Goods Administration)
Cyproterone acetate
Aspen Pharma Pty Ltd
Medicine Registered
CYPROCUR 100 – Consumer Medicine Information Page 1 of 4 Cyprocur 100 _cyproterone acetate _ CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Cyprocur 100. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Cyprocur 100 against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, TALK TO YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again. WHAT CYPROCUR 100 IS USED FOR Cyprocur 100 tablets contain cyproterone acetate as the active ingredient. Cyproterone acetate belongs to a group of medicines called anti- androgens. It blocks the actions of male sex hormones (androgens) which are released naturally in the body. It also reduces the production of androgens. It has been shown that the growth of tumours of the prostate gland may be dependent on male hormones. Since cyproterone acetate blocks the action of androgens and reduces the amount of androgens produced by the body, it can be used to help treat cancer of the prostate gland. It can also be used in conjunction with other medications or following surgical removal of the testes to treat side effects such as “sweats” or “hot flushes” and to prevent any initial worsening of the disease. Cyprocur 100 is for use only in men. This medicine is available only with a doctor's prescription. There is no evidence that Olvassa el a teljes dokumentumot
CYPROCUR 100 – Product Information Page 1 of 9 PRODUCT INFORMATION NAME OF THE MEDICINE CYPROCUR 100 Active: Cyproterone acetate Molecular Formula: C 24 H 29 ClO 4 MW 416.9 CAS: 427-51-0 DESCRIPTION Cyproterone acetate is a white to pale yellow crystalline powder. Cyproterone acetate is very soluble in chloroform and dioxane, freely soluble in acetone and benzene, soluble in ethanol, methanol and ethyl acetate, sparingly soluble in hexane, and almost insoluble in water. Each Cyprocur 100 tablet contains cyproterone acetate 100 mg. Excipients: lactose, maize starch, Povidone, pregelatinised maize starch, magnesium stearate, Colloidal silica. Actions: Anti-androgenic hormone preparation. PHARMACOLOGY Cyproterone acetate inhibits competitively the effect of androgens at androgen dependent target organs, e.g. it shields the prostate from the effect of androgens originating from the gonads and/or the adrenal cortex. Prostatic carcinoma and its metastases are in general androgen dependent, cyproterone acetate therefore exerts a direct anti-androgenic action on the tumour and its metastases. Cyproterone acetate in addition has a progestogenic action exerting a negative feedback effect centrally on the hypothalamic receptors, so leading to a reduction in gonadotropin release, and hence to diminished production of testicular androgens. Treatment with cyproterone acetate in men results in a reduction of sexual drive and potency and inhibition of gonadal function. These changes are reversible following discontinuation of the therapy. CYPROCUR 100 – Product Information Page 2 of 9 The antigonadotropic effect of cyproterone acetate is also exerted when the substance is combined with luteinising hormone releasing hormone (LHRH) agonist Olvassa el a teljes dokumentumot