Država: Kanada
Jezik: engleski
Izvor: Health Canada
CLOPROSTENOL (CLOPROSTENOL SODIUM)
ALIVIRA ANIMAL HEALTH LIMITED
0.25MG
SOLUTION
CLOPROSTENOL (CLOPROSTENOL SODIUM) 0.25MG
INTRAMUSCULAR
100
Prescription
CATTLE
Active ingredient group (AIG) number: 0112396001
APPROVED
2023-08-18
VDD VERSION 00 27JUL2023 Syncroprost Product Insert DIN XXXXXXXX VETERINARY USE ONLY PR SYNCROPROST TM Cloprostenol injection BP Sterile Synthetic Prostaglandin for Cattle DESCRIPTION Cloprostenol sodium is a synthetic prostaglandin analogue, structurally related to prostaglandin F 2 (PGF 2 ). Chemical name: (±)-Sodium (5Z)-7-(1R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3- hydroxybut-1-enyl]-3,5-dihydroxycyclopentylhept-5-enoate. Empirical formula: C 22 H 28 ClNaO 6 , Molecular weight: 446.9 g/mol. Chemical structure: ACTIVE INGREDIENT: Each mL contains Cloprostenol 0.25 mg (equivalent to 0.263 mg of cloprostenol sodium BP). PRESERVATIVE: Chlorocresol 1.0 mg/mL NON-MEDICINAL INGREDIENTS: Ethanol 96%, Sodium citrate, Sodium chloride, Citric acid monohydrate, Water for injections INDICATIONS By its ability to shorten the life span of the _corpus luteum_ (C.L) Syncroprost can be used to treat certain clinical conditions which delay breeding, to manipulate the estrous cycle to better fit certain management practices, and to induce abortion. THERAPEUTIC INDICATIONS SUB-ESTRUS (SILENT HEAT OR NON-DETECTED ESTRUS): Cows which fail to exhibit normal estrous behaviour although ovarian cyclicity continues can be treated Syncroprost while in the luteal phase of the estrous cycle. They may then either be closely observed for estrus over a scheduled time period and bred on detection of estrus or bred at 72 and 96 hours after injection without estrus detection. PYOMETRA OR CHRONIC ENDOMETRITIS: Damage to the reproductive tract at calving or postpartum retention of the placenta frequently leads to infection and inflammation of the uterus which is usually referred to as endometritis. Under certain circumstances, this may progress into chronic endometritis with the uterus becoming distended with purulent matter. This condition, VDD VERSION 00 27JUL2023 frequently referred to as pyometra, is characterized by lack of cyclical estrous behaviour and the presence of a persistent _corpus luteum_ . This condition can be successfully treat Pročitajte cijeli dokument