Hyomide Tablet 10mg

Država: Malezija

Jezik: engleski

Izvor: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktivni sastojci:

HYOSCINE BUTYLBROMIDE

Dostupno od:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

INN (International ime):

HYOSCINE BUTYLBROMIDE

Jedinice u paketu:

500 Tablets; 100 Tablets; 1000 Tablets

Proizveden od:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

Uputa o lijeku

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
1
HYOMIDE TABLET
®
Hyoscine butylbromide (10mg)
WHAT IS IN THE LEAFLET
1.
What Hyomide is used for
2.
How Hyomide works
3.
Before you use Hyomide
4.
How to use Hyomide
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of
Hyomide
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT HYOMIDE IS USED FOR
Hyomide relieves the pain of
stomach and bowel cramps by
helping your digestive system
to relax. It is also used to help
relax gallbladder spasms and
bladder spasms.
HOW HYOMIDE WORKS
Hyomide is known as an
anticholinergic
medicine.
It
reduces
the
wave-like
contractions of smooth muscle
resulting in relief from spasms
in
certain
organs
in
the
digestive system.
Your
doctor
may
have
prescribed
Hyomide
for
another reason.
BEFORE YOU USE HYOMIDE
-
_When you must not take it _
Do not take Hyomide if you are
allergic
to
hyoscine
butylbromide or to any of the
other ingredients listed at the
end of this leaflet.
Some of the symptoms of an
allergic reaction may include:
•
shortness of breath
•
wheezing
or
difficulty
breathing
•
swelling
of
the
face,
lips,
tongue or other parts of the
body
•
rash, itching or hives on the
skin
Do not take Hyomide if you
have:
•
muscle weakness
•
high pressure in the eye
•
porphyria
(a
rare
blood
pigment disorder)
•
fast heart rate
•
enlarged prostate
•
inflammation
of
the
esophagus (food pipe) due to
back flow of stomach acid
•
urinary retention
•
blockage
or
ulcer
in
the
stomach or bowel or in certain
conditions
when
there
is
reduced bowel activity.
These
conditions
are
best
explained
by
your
doctor
or
pharmacist.
Do not take it after the expiry
date printed on the pack or if the
packaging
is
torn
or
shows
signs of tampering.
If it has expired or is damaged,
return it to your pharmacist for
disposal.
If you are not sure whether you
should be given this medicine,
talk to your doctor.
_Pregnancy and lactation _
Do not take Hyomide if you are
pregnant, trying to

Svojstava lijeka

HYOMIDE TABLET 10MG
Hyoscine Butylbromide
DESCRIPTION
A 6.5mm core diameter, round, convex, film coated white tablet marked
'UP' with score on one side.
Each tablet contains Hyoscine Butylbromide 10 mg
INDICATION
Hyomide
tablets
are
indicated
in
spasm
of
the
gastro-intestinal
or
genito-urinary
tracts,
biliary
dyskinesia
and
in
the
prevention
and
treatment of spasmodic dysmenorrhea.
PHARMACODYNAMICS
Hyoscine
N-butylbromide
is
a
quaternary
ammonium
derivative
anticholinergic and has an antispasmodic effect on the organs of the
abdominal and pelvic cavities. It acts by inhibiting the muscarinic
actions
of acetylcholine on structures innervated by postganglionic
cholinergic
nerves as well as on smooth muscles that respond to acetylcholine but
lack cholinergic innervation.
PHARMACOKINETICS
Hyoscine N-butylbromide, a quaternary ammonium compound, is less
lipid soluble than atropine and so may be less likely to cross the
blood-brain barrier; it is also poorly absorbed. In 10 experiments in
3
volunteers, hyoscine butylbromide, in single doses of up to 600mg
taken
as
tablets,
appeared
to
be
inactive
by
mouth;
either
it
remained
unabsorbed or it was absorbed more slowly (10-25%) than it was
inactivated in the body. Hyoscine N-butylbromide, a quaternary ammoni-
um compound is less lipid soluble than atropine and so may be less
likely
to cross the blood-brain barrier; it is also less well absorbed. In 10
experiments in 3 volunteers, hyoscine butylbromide, in single doses of
up
to 600mg taken as tablets, appeared to be inactive by mouth; either it
remained unabsorbed or it was absorbed more slowly (10-25%) than it
was inactivated in the body.
DOSAGE
Adults
Orally : 1 to 2 tablets, three to four times daily.
In dysmenorrhoea, treatment should commence two days before the
expected
onset
of
the
period
and
continue
for
three
days
after
menstruation has begun.
Children 6 -12 years
Orally : 1 tablet three times daily.
OVERDOSAGE
Features
which
may
be
encountered
are
dry
mouth,
loss
of
accommodation,
tachycardia,
orthostatic,
hypote