Država: Novi Zeland
Jezik: engleski
Izvor: Medsafe (Medicines Safety Authority)
Enalapril maleate 10mg
Actavis New Zealand Limited
Enalapril maleate 10 mg
10 mg
Tablet
Active: Enalapril maleate 10mg Excipient: Iron oxide red Iron oxide yellow Lactose monohydrate Magnesium stearate Maize starch Pregelatinised maize starch Sodium bicarbonate
Blister pack, Aluminium/aluminium 30 tablets, 30 tablets
Prescription
Prescription
Neuland Laboratories Limited
Package - Contents - Shelf Life: Blister pack, Aluminium/aluminium - 30 tablets - 24 months from date of manufacture stored at or below 25°C - Blister pack, Aluminium/aluminium - 90 tablets - 24 months from date of manufacture stored at or below 25°C - Bottle, plastic, HDPE 33-40cc, PP cap / induction sealed - 90 tablets - 24 months from date of manufacture stored at or below 25°C - Bottle, plastic, HDPE 35ml, PP cap 28mm induction sealed - 90 tablets - 24 months from date of manufacture stored at or below 25°C
2009-05-11
ARROW - ENALAPRIL _ENALAPRIL MALEATE TABLETS 5MG, 10MG & 20MG _ PRESENTATION 5 mg tablet: White to off-white barrel-shaped tablet with “EL” scoreline “5” on one side and “>” on reverse side. 10 mg tablet: Salmon coloured, barrel-shaped tablet with “EL 10” on one side and “>” on reverse side. 20 mg tablet: Peach coloured, barrel-shaped tablet with “EL 20” on one side and “>” on reverse side. USES _ACTIONS _ Angiotensin converting enzyme (ACE) is a peptidyl dipeptidase which catalyses the conversion of angiotensin I to the pressor substance angiotensin II. After absorption, enalapril is hydrolysed to enalaprilat, which inhibits ACE. Inhibition of ACE results in decreased plasma angiotensin II, which leads to increased plasma renin activity (due to removal of negative feedback of renin release), and decreased aldosterone secretion. ACE is identical to kininase II. Therefore enalapril may also block the degradation of bradykinin, a potent vasodepressor peptide. However, the role that this plays in the therapeutic effects of enalapril remains to be elucidated. While the mechanism through which enalapril lowers blood pressure is believed to be primarily suppression of the renin-angiotensin-aldosterone system, which plays a major role in the regulation of blood pressure, enalapril is anti-hypertensive even in patients with low-renin hypertension. The onset of action of oral enalapril is gradual and smooth; it begins within one hour and its effects usually continue for 24 hours. Consequently, enalapril may be administered on a once-daily basis, with the advantages this brings in convenience and compliance. The Studies of (patients with) Left Ventricular Dysfunction (SOLVD) was a m Pročitajte cijeli dokument