XYLOCAINE- lidocaine hydrochloride injection

देश: संयुक्त राज्य

भाषा: अंग्रेज़ी

स्रोत: NLM (National Library of Medicine)

सक्रिय संघटक:

Lidocaine Hydrochloride (UNII: V13007Z41A) (Lidocaine - UNII:98PI200987)

थमां उपलब्ध:

Rebel Distributors Corp

INN (इंटरनेशनल नाम):

Lidocaine Hydrochloride

रचना:

Lidocaine Hydrochloride 10 mg in 1 mL

प्रशासन का मार्ग:

INFILTRATION

प्रिस्क्रिप्शन प्रकार:

PRESCRIPTION DRUG

चिकित्सीय संकेत:

Xylocaine (lidocaine HCl) Injections are indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks, when the accepted procedures for these techniques as described in standard textbooks are observed. Lidocaine HCl is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

उत्पाद समीक्षा:

Xylocaine (lidocaine HCl) Concentration Epinephrine Dilution (if present) 2 5 10 20 30 10 20 1% X X X X 1% 1:200,000 X 1.5% X X 1.5% 1:200,000 X X 2% X X 2% 1:200,000 X Xylocaine (lidocaine HCl) Concentration Epinephrine Dilution (if present) 2 5 10 20 30 50 0.5% X 1% X X X 1% 1:200,000 X X 1.5% X 1.5% 1:200,000 X X 2% X X 2% 1:200,000 X X Xylocaine (lidocaine HCl) Concentration Epinephrine Dilution (if present) 10 20 50 0.5% X 0.5% 1:200,000 X 1% X X X 1% 1:100,000 X X X 2% X X X 2% 1:100,000 X X All solutions should be stored at room temperature, approximately 25°C (77°F). Protect from light. All trademarks are the property of the AstraZeneca group ©AstraZeneca 2001 AstraZeneca LP, Wilmington, DE 19850 Repackaged by: Rebel Distributors Corp Thousand Oaks, CA 91320

प्राधिकरण का दर्जा:

New Drug Application

उत्पाद विशेषताएं

XYLOCAINE- LIDOCAINE HYDROCHLORIDE INJECTION
REBEL DISTRIBUTORS CORP
----------
XYLOCAINE®
(LIDOCAINE HCL INJECTION, USP)
XYLOCAINE®
(LIDOCAINE HCL AND EPINEPHRINE INJECTION, USP)
FOR INFILTRATION AND NERVE BLOCK
DESCRIPTION
Xylocaine (lidocaine HCl) Injections are sterile, nonpyrogenic,
aqueous solutions that contain a local
anesthetic agent with or without epinephrine and are administered
parenterally by injection. See
INDICATIONS for specific uses.
Xylocaine solutions contain lidocaine HCl, which is chemically
designated as acetamide, 2-
(diethylamino)-N-(2,6- dimethylphenyl)-, monohydrochloride and has the
molecular wt. 270.8.
Lidocaine HCl (C
H N O • HCl) has the following structural formula:
Epinephrine is (-) -3, 4-Dihydroxy-α-[(methylamino) methyl] benzyl
alcohol and has the molecular wt.
183.21. Epinephrine (C H NO ) has the following structural formula:
DOSAGE FORMS LISTED AS XYLOCAINE-MPF INDICATE SINGLE DOSE SOLUTIONS
THAT ARE METHYL PARABEN
FREE (MPF).
Xylocaine MPF is a sterile, nonpyrogenic, isotonic solution containing
sodium chloride. Xylocaine in
multiple dose vials: Each mL also contains 1 mg methylparaben as
antiseptic preservative. The pH of
these solutions is adjusted to approximately 6.5 (5.0-7.0) with sodium
hydroxide and/or hydrochloric
acid.
Xylocaine MPF with Epinephrine is a sterile, nonpyrogenic, isotonic
solution containing sodium
chloride. Each mL contains lidocaine hydrochloride and epinephrine,
with 0.5 mg sodium metabisulfite
as an antioxidant and 0.2 mg citric acid as a stabilizer. Xylocaine
with Epinephrine in multiple dose
vials: Each mL also contains 1 mg methylparaben as antiseptic
preservative. The pH of these solutions
is adjusted to approximately 4.5 (3.3-5.5) with sodium hydroxide
and/or hydrochloric acid. Filled under
nitrogen.
CLINICAL PHARMACOLOGY
MECHANISM OF ACTION:
Lidocaine HCl stabilizes the neuronal membrane by inhibiting the ionic
fluxes required for the initiation
and conduction of impulses thereby effecting local anesthetic action.
HEMODYNAMICS :
14
22
2