देश: दक्षिण अफ़्रीका
भाषा: अंग्रेज़ी
स्रोत: South African Health Products Regulatory Authority (SAHPRA)
Geoschw
SPECTRAMOX SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form): SPECTRAMOX SPECTRAMOX C 250 CAPSULES SPECTRAMOX S 125 POWDER FOR SUSPENSION SPECTRAMOX SF 250 POWDER FOR SUSPENSION COMPOSITION: Amoxycillin trihydrate available as: Spectramox C 250 - Gelatin capsules containing the equivalent of 250 mg amoxycillin. Spectramox S 125 - Each 5 mL of the reconstituted suspension contains the equivalent of 125 mg amoxycillin. Spectramox SF 250 - Each 5 mL of the reconstituted suspension contains the equivalent of 250 mg amoxycillin. PHARMACOLOGICAL CLASSIFICATION: A20.1.2 Penicillins. PHARMACOLOGICAL ACTION: Amoxycillin is a penicillinase-susceptible penicillin. Amoxycillin exhibits in vitro bactericidal activity against a wide range of Gram-negative and Gram-positive organisms including: (in vitro sensitivity does not necessarily imply in vivo efficacy). Gram-positive bacteria: Gram-negative bacteria: * Staphylococcus aureus (Penicillin-sensitive) Neisseria gonorrhoeae Streptococcus pyogenes Neisseria meningitidis * Streptococcus viridans Haemophilus influenzae * Streptococcus faecalis (except type b-strains causing meningitis in children) * Streptococcus pneumoniae Bordetella pertussis * Corynebacterium species * Escherichia coli * Clostridium species Salmonella typhi * Bacillus anthracis Salmonella species Shigella species Proteus mirabilis * Sensitivity tests must be performed Amoxycillin is well absorbed orally. After oral administration, there is no significant difference between the peak serum levels in fasting and non-fasting subjects. The presence of food does not interfere with the absorption of amoxycillin. Amoxycillin may, therefore, be taken with meals. There is insufficient evidence at present to show that amoxycillin penetrates into the cerebro-spinal fluid in therapeutic qua पूरा दस्तावेज़ पढ़ें