SEVOFLURANE - sevoflurane liquid

देश: संयुक्त राज्य

भाषा: अंग्रेज़ी

स्रोत: NLM (National Library of Medicine)

सक्रिय संघटक:

SEVOFLURANE (UNII: 38LVP0K73A) (SEVOFLURANE - UNII:38LVP0K73A)

थमां उपलब्ध:

Patterson Veterinary

प्रशासन का मार्ग:

RESPIRATORY (INHALATION)

प्रिस्क्रिप्शन प्रकार:

PRESCRIPTION

चिकित्सीय संकेत:

Sevoflurane is indicated for induction and maintenance of general anesthesia in dogs. Sevoflurane is contraindicated in dogs with a known sensitivity to sevoflurane or other halogenated agents.

उत्पाद समीक्षा:

Sevoflurane is packaged in 250 mL amber-colored bottles. 250 ML - NDC 14043-110-25 Store at 20° to 25°C (68° to 77°F); excursions permitted to 15°C-30°C (59°F-86°F) [See USP Controlled Room Temperature].

प्राधिकरण का दर्जा:

Abbreviated New Animal Drug Application

उत्पाद विशेषताएं

SEVOFLURANE - SEVOFLURANE LIQUID
PATTERSON VETERINARY
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DESCRIPTION
Inhalation Anesthetic For Use in Dogs
Caution: Federal law restricts this drug to use by or on the order of
a licensed veterinarian.
Sevoflurane, a volatile liquid, is a halogenated general inhalation
anesthetic drug. Its chemical name is
fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether, and its
structural formula is:
Sevoflurane Physical Constants are:
Molecular weight 200.05
Boiling point at 760 mm Hg 58.6°C
Specific gravity at 20°C 1.520-1.525 g/mL
Vapor pressure in mm Hg at 20°C 157
at 25°C 197
at 36°C 317
Distribution Partition Coefficients at 37°C:
Blood/Gas 0.63-0.69
Water/Gas 0.36
Olive Oil/Gas 47-54
Brain/Gas 1.15
Mean Component/Gas Partition Coefficients at 25°C for Polymers Used
Commonly in Medical
Applications:
Conductive rubber 14.0
Butyl rubber 7.7
Polyvinyl chloride 17.4
Polyethylene 1.3
Sevoflurane is nonflammable and nonexplosive as defined by the
requirements of International
Electrotechnical Commission 601-2-13.
Sevoflurane is a clear, colorless, stable liquid containing no
additives or chemical stabilizers.
Sevoflurane is nonpungent. It is miscible with ethanol, ether,
chloroform and petroleum benzene, and it
is slightly soluble in water. Sevoflurane is stable when stored under
normal room lighting condition
according to instructions.
INDICATIONS
Sevoflurane is indicated for induction and maintenance of general
anesthesia in dogs.
DOSAGE AND ADMINISTRATION
INSPIRED CONCENTRATION: The delivered concentration of Sevoflurane
should be known. Since the depth
of anesthesia may be altered easily and rapidly, only vaporizers
producing predictable percentage
concentrations of sevoflurane should be used. Sevoflurane should be
vaporized using a precision
vaporizer specifically calibrated for sevoflurane. Sevoflurane
contains no stabilizer. Nothing in the
drug product alters calibration or operation of these vaporizers. The
administration of general
anesthesia must be individualized based on the patient's resp