देश: ऑस्ट्रेलिया
भाषा: अंग्रेज़ी
स्रोत: Department of Health (Therapeutic Goods Administration)
pioglitazone hydrochloride
Amneal Pharma Australia Pty Ltd
Pioglitazone hydrochloride
Registered
_Pioglitazone AN tablets – Consumer Medicine Information _ _ _ _Doc ID: 88.AN.M.2.0 _ _ _ _ _ _Page 1 _ PIOGLITAZONE AN TABLETS _Pioglitazone Hydrochloride _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about PIOGLITAZONE AN. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking PIOGLITAZONE AN against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, TALK TO YOUR DOCTOR OR PHARMACIST. Keep this leaflet with your medicine. You may need to read it again. WHAT PIOGLITAZONE AN IS USED FOR PIOGLITAZONE AN is a tablet that is used to improve the action of the body's naturally produced insulin. PIOGLITAZONE AN is used in the management of type 2 diabetes not controlled by diet. PIOGLITAZONE AN helps to control the level of glucose in your blood when you have type 2 diabetes. This is the 'adult onset' type of diabetes and is controlled by diet, certain oral medications and occasionally insulin. This medicine is also called pioglitazone hydrochloride and belongs to a group of medicines called glitazones. Glitazones decrease insulin resistance. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. PIOGLITAZONE AN can be used alone (when diet and exercise is not enough to treat your diabetes) or together with other anti-diabetic medicines. This medicine is available only with a doctor's prescription. The use of PIOGLITAZONE AN has not been studied in children . BEFORE YOU TAKE PIOGLITAZONE AN _WHEN YOU MUST NOT TAKE _ _PIOGLITAZONE AN _ DO NOT TAKE PIOGLITAZONE AN IF: YOU HAVE HEART FAILURE REQUIRING TREATMENT. TALK TO YOUR DOCTOR IF YOU HAVE HEART FAILURE YOU HAVE TYPE 1 DIABETES OR DIABETIC KETOACIDOSIS (OFTEN CAUSED B VERY HIGH BLOOD GLUCOSE LEVELS) YOU HAVE H पूरा दस्तावेज़ पढ़ें
_Pioglitazone AN tablets Product Information _ _ _ _ _ _ _ _ Amneal Pharma Australia Pty Ltd _ Pioglitazone AN.PI v3.0 Page 1 PIOGLITAZONE AN _ _ _(PIOGLITAZONE TABLETS) _ _ _ PRODUCT INFORMATION _ _ NAME OF THE MEDICINE The active ingredient in PIOGLITAZONE AN tablets is pioglitazone hydrochloride. CHEMICAL NAME: (±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride MOLECULAR FORMULA: C 19 H 20 N 2 O 3 S. HCl MOLECULAR WEIGHT: 392.90 CAS REGISTRY NUMBER: _[112529-15-4]_ DESCRIPTION Pioglitazone is off-white to pale yellow colour powder. It is soluble in methanol, practically insoluble in water. PIOGLITAZONE AN is available as tablets containing 15, 30 & 45 mg pioglitazone as hydrochloride. PIOGLITAZONE AN tablets contain the following inactive ingredients: Lactose, carmellose calcium, hydroxypropylcellulose and magnesium stearate. PHARMACOLOGY Pioglitazone is an oral antidiabetic agent that acts primarily by decreasing insulin resistance. Pharmacological studies indicate that pioglitazone improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Pioglitazone improves glycaemic control while reducing circulating insulin levels. Fasting and postprandial glycaemic control are improved in patients with type 2 diabetes mellitus. The decreased insulin resistance produced by pioglitazone results in lower blood glucose concentrations, lower plasma insulin levels and lower HbA 1c values. _Pioglitazone AN tablets Product Information _ _ _ _ _ _ _ _ Amneal Pharma Australia Pty Ltd _ Pioglitazone AN.PI v3.0 Page 2 MODE OF ACTION Pioglitazone is a thiazolidinedione antidiabetic agent that depends on the presence of insulin for its unique mechanism of action. Pioglitazone decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. Unlike sulfonylureas, pioglitazone is not an insulin secretagogue. Pioglitazone is a potent and highly selective agonist पूरा दस्तावेज़ पढ़ें