METHODYNE INJECTION

देश: ऑस्ट्रेलिया

भाषा: अंग्रेज़ी

स्रोत: APVMA (Australian Pesticides and Veterinary Medicines Authority)

सक्रिय संघटक:

METHADONE HCL

थमां उपलब्ध:

JUROX PTY LIMITED

INN (इंटरनेशनल नाम):

methadone HCl(10mg/mL)

फार्मास्यूटिकल फॉर्म:

PARENTERAL LIQUID/SOLUTION/SUSPENSION

रचना:

METHADONE HCL UNGROUPED Active 10.0 mg/ml

पैकेज में यूनिट:

20 mL

वर्ग:

VM - Veterinary Medicine

चिकित्सीय समूह:

DOG | HORSE | BITCH | CASTRATE | COLT | DONKEY | ENDURANCE HORSE | FILLY | FOAL | GELDING | HIGH PERFORMANCE HORSES | HORSES AT

चिकित्सीय क्षेत्र:

ANAESTHETICS/ANALGESICS

चिकित्सीय संकेत:

ANALGESIC | PRE-ANAESTHETIC | RESTRAINT | ANAESTHETIC PREMEDICANT | ANTIPYRETIC | COLIC | MUSCLE RELAXANT | SEDATIVE | SPASMOLYTIC

उत्पाद समीक्षा:

Poison schedule: 8; Withholding period: WHP Meat (Horses): NOT TO BE USED in h orses intented for human consumption.; Host/pest details: CAT: [ANALGESIC, PRE-ANAESTHETIC]; DOG: [ANALGESIC, PRE-ANAESTHETIC]; HORSE: [ANALGESIC, RESTRAINT]; Poison schedule: 8; Withholding period: ; Host/pest details: CAT: [ANALGESIC, PRE-ANAESTHETIC]; DOG: [ANALGESIC, PRE-ANAESTHETIC]; HORSE: [ANALGESIC, RESTRAINT]; For use only by a registered veterinarian. For analgesia and restraint in horses, and analgesia and anaesthetic premedication in dogs and cats.See Restraints, Contraindications and Precautions on label.

प्राधिकरण का दर्जा:

Registered

प्राधिकरण की तारीख:

2023-07-01

सूचना पत्रक

+
RLP
APPROVED
COMPANY NAME:
JUROX PTY LIMITED
PRODUCT NAME:
METHODYNE INJECTION
APVMA APPROVAL
NO:
64300/1
00469
I
LABEL
NAME:
METHODYNE INJECTION
SIGNAL HEADINGS:
CONTROLLED DRUG
CONSTITUENT
STATEMENTS:
CLAIMS:
I
NET CONTENTS:
DIRECTIONS FOR
USE:
RESTRAINTS:
CONTRAINDICATIONS:
PRECAUTIONS:
KEEP OUT OF REACH OF CHILDREN
FORANIMAL
TREATMENT ONLY
POSSESSION WITHOUT AUTHORITY ILLEGAL
10 mg/mL METHADONE HYDROCHLORIDE
For use only by a registered veterinarian.
For analgesia and restraint in horses, and analgesia and anaesthetic
premedication
in
dogs
and cats.
20mL
READ THE ENCLOSED LEAFLET BEFORE USING THIS PRODUCT.
DO NOT USE
in
food-producing species
of
animals.
DO NOT USE
in
horses intended for human consumption.
This product is contraindicated for use in animals during parturition.
This product is contraindicated for use in animals with respiratory
depression.
This product is contraindicated for use in pregnant, breeding or
lactating cats, as safe use
of the product in these animals has not been evaluated.
Use with caution in animals with hypothyroidism, adrenocortical
insufficiency, impaired
renal and hepatic function, and shock.
Safe use of this formulation
in
cats less than one year of age has not been established.
Published information supports the safe and effective use
of
methadone
in
cats older than
6 months of age.
I
SIDE EFFECTS:
DOSAGE AND
ADMINISTRATION:
GENERAL DIRECTIONS:
Use the contents within 28 days of first broaching
of
the vial. Discard the unused portion.
Horses:
Analgesia: 0.22 mg/kg
(1
0
ml/450
kg) bodyweight by intramuscular or subcutaneous
injection.
Restraint: 0.11 mg/kg (5
ml/450
kg) bodyweight combined with 0.055 mg/kg bodyweight
acetylpromazine (2.5 mL
of
10
mg/mL acetylpromazine per 450 kg) by intravenous
injection.
Dogs:
Analgesia:
0.11
-
0.55 mg/kg
(0.11
-
0.55
ml/1
0 kg) bodyweight by intramuscular
or
subcutaneous injection.
Premedication:
1.1
mg/kg
(1.1
ml/1
0 kg) bodyweight by subcutaneous injection.
Cats:
Analgesia:
0.2-
0.6 mg/kg
(0.2-
0.6
ml/10
kg) bodyweight by subcutaneous i

उत्पाद विशेषताएं

METHODYNE INJECTION
Page 1 of 6
ISSUED:
21 DECEMBER 2015
SAFETY DATA SHEET
SECTION 1: IDENTIFICATION OF CHEMICAL PRODUCT AND COMPANY
PRODUCT NAME:
METHODYNE INJECTION
PRODUCT CODE:
503760 (20 mL)
RECOMMENDED USE:
For analgesia and restraint in horses, and analgesia and
anaesthetic premedication in dogs and cats.
RESTRICTIONS ON USE:
For animal treatment only.
COMPANY IDENTIFICATION:
Jurox Pty Limited
ADDRESS:
85 Gardiner Street
Rutherford NSW 2320
Australia
EMAIL:
[e-mail]
CUSTOMER CENTRE:
1800 023 312
NATIONAL POISONS INFORMATION CENTRE:
13 1126 (Australia-wide)
EMERGENCY TELEPHONE NUMBER:
1800 023 312 (9am – 5pm, Monday to Friday)
SECTION 2: HAZARDS IDENTIFICATION
This product has been assessed according to GHS and is classified as
follows:
GHS CATEGORY
HAZARD CODE
HAZARD STATEMENT
STOT – RE Category 2
H373
May cause damage to organs through prolonged or
repeated exposure
Chronic aquatic hazard Category 3
H412
Harmful to aquatic life with long lasting effects
SIGNAL WORD:
WARNING
GHS PICTOGRAMS:
Health hazard
PRECAUTIONARY STATEMENTS:
Prevention
P260 Do not breathe vapours.
P273 Avoid release to the environment.
Response
P314 Get medical advice if you feel unwell.
P391 Collect spillage.
Disposal
P501 Dispose of empty container by wrapping with paper and putting in
garbage. Return unused expired
product to pharmacy or pharmacy inspector.
METHODYNE INJECTION
Page 2 of 6
SECTION 3: COMPOSITION / INFORMATION ON INGREDIENTS
INGREDIENT
CAS NO.
CONTENT
Methadone hydrochloride
125-56-4
1%
Ingredients not contributing to the hazards
> 90%
SECTION 4: FIRST AID MEASURES
GENERAL INFORMATION: RESPIRATORY DEPRESSION, SYSTEMIC HYPOTENSION,
RESPIRATORY ARREST, SHOCK,
CARDIAC ARREST AND DEATH MAY OCCUR. CONSULT THE NATIONAL POISONS
CENTRE ON 13 1126 OR A DOCTOR
IMMEDIATELY IN EVERY CASE OF SUSPECTED CHEMICAL POISONING. Never give
fluids or induce vomiting if a
patient is unconscious or convulsing regardless of cause of injury. If
medical advice/attention is needed, have
this SDS, product container or label at hand.

सुरक्षा डाटा शीट

WWW.JUROX.COM.AU
Customer Service 1800 023 312
TECHNICAL NOTES
METHODYNE
®
Injection
ACTIVE CONSTITUENTS
Methadone hydrochloride 10 mg/mL
ACTIONS
Methadone is a potent morphine analogue neuroleptanalgesic which
raises the pain threshold by binding to the μ-opiate receptors.
Methadone is pharmacologically similar to morphine.
Methadone depresses the respiratory centre of the medulla and
stimulates the vagal centre, resulting in reduced respiratory rate
and minute volume, and bradycardia. Intestinal tonus is increased.
Convulsions and respiratory depression are seen at ten times the
therapeutic dose.
Methadone is detectable in plasma within 10 minutes of subcutaneous
injection. Firm protein binding appears to occur in various
tissues including the brain. Methadone undergoes extensive liver
biotransformation and metabolites are predominantly excreted in
bile and urine, together with small amounts of unchanged drug.
The narcotic action of methadone is antagonised by naloxone.
INDICATIONS
For analgesia and restraint in horses, and analgesia and anaesthetic
premedication in dogs and cats.
DOSAGE AND ADMINISTRATION
Refer to the product leaflet for full dosage and administration
instructions
HORSES:
ANALGESIA: 0.22 mg/kg (10 mL/450 kg) bodyweight by intramuscular or
subcutaneous injection.
RESTRAINT: 0.11 mg/kg (5 mL/450 kg) bodyweight combined with 0.055
mg/kg bodyweight acetylpromazine (2.5 mL of 10 mg/mL
acetylpromazine per 450 kg) by intravenous injection.
WWW.JUROX.COM.AU
Customer Service 1800 023 312
® Registered Trademark of Jurox Pty Ltd
TECHNICAL NOTES
DOGS:
ANALGESIA: 0.11 – 0.55 mg/kg (0.11 – 0.55 mL/10 kg) bodyweight by
intramuscular or subcutaneous injection.
PREMEDICATION: 1.1 mg/kg (1.1 mL/10 kg) bodyweight by subcutaneous
injection.
CATS:
ANALGESIA: 0.2 - 0.6 mg/kg (0.2 - 0.6 mL/10 kg) bodyweight by
subcutaneous injection.
PREMEDICATION: 0.2 - 0.6 mg/kg (0.2 - 0.6 mL/10 kg) bodyweight by
subcutaneous injection.
REPEAT ANALGESIA: 0.2 - 0.6 mg/kg (0.2 - 0.6 mL/10 kg) bodyweight by
subcutaneous inject