KLOR-CON EXTENDED-RELEASE- potassium chloride tablet, extended release

देश: संयुक्त राज्य

भाषा: अंग्रेज़ी

स्रोत: NLM (National Library of Medicine)

सक्रिय संघटक:

Potassium Chloride (UNII: 660YQ98I10) (Potassium cation - UNII:295O53K152)

थमां उपलब्ध:

Contract Pharmacy Services-PA

INN (इंटरनेशनल नाम):

Potassium Chloride

रचना:

Potassium Chloride 750 mg

प्रशासन का मार्ग:

ORAL

प्रिस्क्रिप्शन प्रकार:

PRESCRIPTION DRUG

चिकित्सीय संकेत:

BECAUSE OF REPORTS OF INTESTINAL AND GASTRIC ULCERATION AND BLEEDING WITH EXTENDED-RELEASE POTASSIUM CHLORIDE PREPARATIONS, THESE DRUGS SHOULD BE RESERVED FOR THOSE PATIENTS WHO CANNOT TOLERATE OR REFUSE TO TAKE LIQUID OR EFFERVESCENT POTASSIUM PREPARATIONS OR FOR PATIENTS IN WHOM THERE IS A PROBLEM OF COMPLIANCE WITH THESE PREPARATIONS. - For the therapeutic use of patients with hypokalemia, with or without metabolic alkalosis; in digitalis intoxication; and in patients with hypokalemic familial periodic paralysis. If hypokalemia is the result of diuretic therapy, consideration should be given to the use of a lower dose of diuretic, which may be sufficient without leading to hypokalemia. - For the prevention of hypokalemia in patients who would be at particular risk if hypokalemia were to develop, e.g., digitalized patients or patients with significant cardiac arrhythmias. The use of potassium salts in patients receiving diuretics for uncomplicated essential hypertension is often unnecessary when such patien

उत्पाद समीक्षा:

Film-coated Klor-Con® 10 (yellow, debossed with “KC 10”), round tablets containing: Store at controlled room temperature, 15-30°C (59-86°F). Protect from light and moisture. Dispense in a tight container with child-resistant closure. Manufactured by UPSHER-SMITH LABORATORIES, INC. Minneapolis, MN 55447 Revised 1008 Repackaged by: Contract Pharmacy Services-PA 125 Titus Ave Suite 200 Warrington, PA 18976 USA Original--04/2010--NJW

प्राधिकरण का दर्जा:

New Drug Application

उत्पाद विशेषताएं

KLOR-CON EXTENDED-RELEASE- POTASSIUM CHLORIDE TABLET, EXTENDED RELEASE
CONTRACT PHARMACY SERVICES-PA
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KLOR-CON
POTASSIUM CHLORIDE EXTENDED-RELEASE TABLETS, USP
10 MEQ
DESCRIPTION
Klor-Con Extended-release Tablets, USP are a solid oral dosage form of
potassium chloride. Each
contains 600 mg or 750 mg of potassium chloride equivalent to 8 mEq or
10 mEq of potassium in a wax
matrix tablet. This formulation is intended to provide an
extended-release of potassium from the matrix
to minimize the likelihood of producing high, localized concentrations
of potassium within the
gastrointestinal tract.
Klor-Con Extended-release Tablets are an electrolyte replenisher. The
chemical name is potassium
chloride, and the structural formula is KCl. Potassium chloride, USP
is a white, granular powder or
colorless crystals. It is odorless and has a saline taste. Its
solutions are neutral to litmus. It is freely
soluble in water and insoluble in alcohol.
_Inactive Ingredients:_ Hydrogenated vegetable oil, magnesium
stearate, polyethylene glycol, polyvinyl
alcohol, silicon dioxide, talc and titanium dioxide. Yellow tablets
also contain D&C Yellow No. 10
aluminum lake and FD&C Yellow No. 6 aluminum lake. Blue tablets also
contain FD&C Blue No. 1
aluminum lake and FD&C Blue No. 2 aluminum lake.
CLINICAL PHARMACOLOGY
The potassium ion is the principal intracellular cation of most body
tissues. Potassium ions participate
in a number of essential physiological processes including the
maintenance of intracellular tonicity, the
transmission of nerve impulses, the contraction of cardiac, skeletal
and smooth muscle and the
maintenance of normal renal function.
The intracellular concentration of potassium is approximately 150 to
160 mEq per liter. The normal
adult plasma concentration is 3.5 to 5 mEq per liter. An active ion
transport system maintains this gradient
across the plasma membrane.
Potassium is a normal dietary constituent and under steady state
conditions the amount of potassium
absorbed from the gastrointestinal tract is e