देश: मलेशिया
भाषा: अंग्रेज़ी
स्रोत: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
NAPROXEN SODIUM
DYNAPHARM (M) SDN BHD
NAPROXEN SODIUM
500 Tablets
DYNAPHARM (M) SDN BHD
DYNAFLEX TABLET Naproxen Sodium (275 mg, 550 mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What DYNAFLEX is used for 2. How DYNAFLEX works 3. Before you use DYNAFLEX 4. How to use DYNAFLEX 5. While you are using it 6. Side effects 7. Storage and Disposal of DYNAFLEX 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision 11. Serial number WHAT DYNAFLEX IS USED FOR For rheumatic disorders, mild to moderate pain and in acute gout. HOW DYNAFLEX WORKS Naproxen is a non-steroidal anti- inflammatory drug (NSAID) with pain relieving and fever reducing properties. BEFORE YOU USE DYNAFLEX - _When you must not use it _ Do not use this medicine in: - Individuals allergic to Aspirin and Naproxen - Individuals in whom Aspirin or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) induce asthma, rhinitis or urticaria. - Peptic ulcer. _Pregnancy and lactation _ Do not take DYNAFLEX if you are pregnant, trying to get pregnant or think you may be pregnant. Do not take DYNAFLEX if you are breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. - _Before you start use it _ Tell your doctor or pharmacist if you have 1. Blood clot in heart and blood vessels 2. High blood pressure 3. Heart failure 4. Stomach and intestine problems 5. Severe skin reactions - _Taking other medicines _ Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. HOW TO USE DYNAFLEX - _How much to use _ Take the medication orally, with or after meals._ _ The daily dose should not exceed 1375 mg. Not recommended for use in children under 16 years of age. There is a greater risk of NSAID-induced gastrointestinal bleeding in the elderly. It is therefore recommended that individuals in this age group, especially those 70 years of age or older, be given half the usual adult dose initially. After assessing the risk/benefit ratio in each individual patient, the lowest पूरा दस्तावेज़ पढ़ें
DYNAFLEX DESCRIPTION CONTENT DYNAFLEX TABLET 275MG MAL05051065AZ TABLET Colour : Light Blue Shape : Oval and Biconvex Each Tablet Contains: Naproxen Sodium 275 mg Equivalent To Naproxen 250 mg DYNAFLEX TABLET 550MG MAL19950335AZ TABLET Colour : White Shape : Oblong Each Tablet Contains: Naproxen Sodium 550 mg Equivalent To Naproxen 500 mg PHARMACODYNAMICS: Naproxen is a non-steroidal anti-inflammatory analgesic compound with antipyretic properties as has been demonstrated in classical animal test systems. Naproxen exhibits its anti-inflammatory effect even in adrenalectomised animals, indicating that its action is not mediated through the pituitary-adrenal axis. Naproxen inhibits prostaglandin synthetase (as do other NSAIDs). As with other NSAIDs, however, the exact mechanism of its anti-inflammatory action is not known. PHARMACOKINETICS: Naproxen is completely absorbed from the gastrointestinal tract, and peak plasma levels are reached in 2 to 4 hours. Naproxen is present in the blood mainly as unchanged drug, extensively bound to plasma proteins. The plasma half-life is between 12 and 15 hours, enabling a steady state to be achieved within 3 days of initiation of therapy on a twice daily dose regimen. The degree of absorption is not significantly affected by either foods or most antacids. Excretion is almost entirely via the urine, mainly as conjugated Naproxen, with some unchanged drug. Metabolism in children is similar to that in adults. Chronic alcoholic liver disease reduces the total plasma concentration of Naproxen but the concentration of unbound Naproxen increases. In the elderly, the unbound plasma concentration of Naproxen is increased although total plasma concentration is unchanged. INDICATION: For rheumatic disorders such as ankylosing spondylitis, osteoarthritis and rheumatoid arthritis. Mild to moderate pain such as dysmenorrhoea, migraine and some musculoskeletal disorders and in acute gout. RECOMMENDED DOSE: Take the medication orally, with or after meals. Dysmenorrhoea, pain following IUD inse पूरा दस्तावेज़ पढ़ें