DUVOID TABLET

देश: कनाडा

भाषा: अंग्रेज़ी

स्रोत: Health Canada

सक्रिय संघटक:

BETHANECHOL CHLORIDE

थमां उपलब्ध:

PALADIN LABS INC.

ए.टी.सी कोड:

N07AB02

INN (इंटरनेशनल नाम):

BETHANECHOL

डोज़:

10MG

फार्मास्यूटिकल फॉर्म:

TABLET

रचना:

BETHANECHOL CHLORIDE 10MG

प्रशासन का मार्ग:

ORAL

पैकेज में यूनिट:

100

प्रिस्क्रिप्शन प्रकार:

Prescription

चिकित्सीय क्षेत्र:

PARASYMPATHOMEMETIC (CHOLINERGIC) AGENTS

उत्पाद समीक्षा:

Active ingredient group (AIG) number: 0107779001; AHFS:

प्राधिकरण का दर्जा:

APPROVED

प्राधिकरण की तारीख:

2000-03-10

उत्पाद विशेषताएं

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PRESCRIBING INFORMATION
PR DUVOID
® (bethanechol chloride)
10MG, 25MG AND 50MG TABLETS, USP
PARASYMPATHOMIMETIC
Paladin Labs Inc.
Date of preparation:
6111 Royalmount Avenue, Suite 102
May 21, 2009
Montreal, Quebec
H4P 2T4
Control No.: 130078
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PRESCRIBING INFORMATION
PR DUVOID
®
(bethanechol chloride)
10, 25 AND 50 MG TABLETS, USP
PARASYMPATHOMIMETIC
ACTIONS AND CLINICAL PHARMACOLOGY
Bethanechol acts principally by producing the effects of stimulation
of the parasympathetic
nervous system. It increases the tone of the detrusor urinae muscle,
usually producing a
contraction sufficiently strong to initiate micturition and empty the
bladder. It stimulates
gastric motility, increases gastric tone, and often restores rhythmic
peristalsis.
Stimulation of the parasympathetic nervous system releases
acetylcholine at the nerve
endings. When spontaneous stimulation is reduced and therapeutic
intervention is required,
acetylcholine can be given, but it is rapidly hydrolyzed by
cholinesterase, and its effects are
transient. Bethanechol is not destroyed by cholinesterase and its
effects are more prolonged
and predictable than those of acetylcholine.
It has predominant muscarinic action and only feeble nicotinic action.
Doses that stimulate
micturition and defecation and increase peristalsis do not ordinarily
stimulate ganglia or
voluntary muscles. Therapeutic test doses in normal human subjects
have little effect on
heart rate, blood pressure, or peripheral circulation.
INDICATIONS AND CLINICAL USE
The treatment of acute postoperative and postpartum nonobstructive
(functional) urinary
retention and for neurogenic atony of the urinary bladder with
retention.
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CONTRAINDICATIONS
Hyperthyroidism,
pregnancy,
lactation,
peptic
ulcer,
latent
or
active
bronchial
asthma,
pronounced bradycardia or hypotension, vasomotor instability, coronary
artery disease,
epilepsy, parkinsonism.
Should not be employed when the strength or integrity of the
gastrointestinal or bladder wall
is in question, or in the presence of