Ciprofloxacin (Rex)
देश: न्यूज़ीलैंड
भाषा: अंग्रेज़ी
स्रोत: Medsafe (Medicines Safety Authority)
उत्पाद विशेषताएं
(SPC)
02-04-2013
अनुरोध भेजा।
सक्रिय संघटक:
Ciprofloxacin hydrochloride 582.16mg equivalent to ciprofloxacin base 500 mg;
थमां उपलब्ध:
REX Medical Ltd
INN (इंटरनेशनल नाम):
Ciprofloxacin hydrochloride 582.16 mg (equivalent to ciprofloxacin base 500 mg)
डोज़:
500 mg
फार्मास्यूटिकल फॉर्म:
Film coated tablet
रचना:
Active: Ciprofloxacin hydrochloride 582.16mg equivalent to ciprofloxacin base 500 mg Excipient: Colloidal silicon dioxide Croscarmellose sodium Hypromellose Purified talc Croscarmellose sodium Macrogol 6000 Magnesium stearate Microcrystalline cellulose Povidone Propylene glycol Purified talc Titanium dioxide
पैकेज में यूनिट:
Blister pack, PVC/aluminium foil blisters, 30 tablets
वर्ग:
Prescription
प्रिस्क्रिप्शन प्रकार:
Prescription
द्वारा बनाया गया:
Marksans Pharma Limited
उत्पाद समीक्षा:
Package - Contents - Shelf Life: Blister pack, PVC/aluminium foil blisters - 30 tablets - 36 months from date of manufacture stored at or below 25°C
प्राधिकरण की तारीख:
2003-05-27
उत्पाद विशेषताएं
NEW ZEALAND DATASHEET
NAME OF MEDICINE
CIPROFLOXACIN
Ciprofloxacin hydrochloride tablets
PRESENTATION
Ciprofloxacin tablets 250 mg: white, circular, biconvex, film-coated tablet, with a score and
“CP 250” embossed on one side and plain on the other.
Ciprofloxacin tablets 500 mg: white, capsule shaped, film-coated tablet, with a score and
“CPX 500” embossed on one side
and “NEO embossed on the other.
Ciprofloxacin tablets 750 mg: white, capsule shaped, film-
coated tablet, with “CPX 750”
embossed on one
side and “NEO embossed on the other.
Do not halve the tablet. Dose equivalence when the tablet is divided has not been
established.
USES
ACTIONS
Ciprofloxacin is
a synthetic broad spectrum antibacterial agent (ATCCODE: J 01 MA 02).
MECHANISM OF ACTION
Ciprofloxacin is effective in-vitro against a wide range of Gram-negative and Gram-positive
organisms. The bactericidal action of ciprofloxacin results from inhibition of bacterial type II
topoisomerases (DNA gyrase and topoisomerase IV), which are required for bacterial DNA
replication, transcription, repair, and recombination.
MECHANISM OF RESISTANCE
_In vitro _resistance to ciprofloxacin is commonly due to mutations in bacterial topoisomerases
and DNA gyrase through multiple-step mutations. Single mutations may result in reduced
susceptibility rather than clinical resistance, but multiple mutations generally result in clinical
resistance to ciprofloxacin and cross-resistance
across the quinolone class.
Resistance mechanisms that inactivate other antibiotics such as permeation barriers
(common
पूरा दस्तावेज़ पढ़ें
