APO-GABAPENTIN Gabapentin 100mg Capsule bottle

देश: ऑस्ट्रेलिया

भाषा: अंग्रेज़ी

स्रोत: Department of Health (Therapeutic Goods Administration)

सक्रिय संघटक:

gabapentin

थमां उपलब्ध:

Apotex Pty Ltd

INN (इंटरनेशनल नाम):

Gabapentin

प्राधिकरण का दर्जा:

Registered

सूचना पत्रक

APO-GABAPENTIN
CAPSULES
_Contains the active ingredient gabapentin_
CONSUMER MEDICINE INFORMATION
_FOR A COPY OF A LARGE PRINT LEAFLET, PH: 1800 195 055_
WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about gabapentin. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
your medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST IF:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
You can also download the most up
to date leaflet from
www.apotex.com.au.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT IS THIS MEDICINE
USED FOR
The name of your medicine is APO-
Gabapentin Capsules. It contains the
active ingredient, gabapentin.
It is used to:
•
control epilepsy, a condition that
causes repeated seizures (fits).
There are many different types of
seizures, ranging from mild to
severe
•
treat neuropathic pain (pain due
to nerves being damaged or
affected).
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed it for
another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Gabapentin belongs to a group of
medicines called anticonvulsants.
It is thought to work by controlling
brain chemicals which send signals
to nerves to help control seizures or
neuropathic pain.
This medicine helps to relieve pain.
Your doctor may prescribe
gabapentin in addition to your
current treatment when y

उत्पाद विशेषताएं

Product Information – Australia
APO- Gabapentin Capsules
Page 1
APO-GABAPENTIN CAPSULES
NAME OF THE MEDICINE
Gabapentin.
Chemical Name:
1-(aminomethyl) cyclohexaneacetic acid.
Structural formula:
Chemical Formula:
C
9
H
17
NO
2
Molecular Weight:
171.24
CAS Registry Number:
60142-96-3
DESCRIPTION
Gabapentin is a white to off-white crystalline solid. It is freely
soluble in water and in both basic and
acidic aqueous solutions.
Each capsule contains 100mg, 300mg or 400mg gabapentin, as the active
ingredient.
In
addition,
each
capsule
contains
the
following
inactive
ingredients:
croscarmellose
sodium,
magnesium stearate, purified talc (300mg & 400mg only), titanium
dioxide, gelatin, iron oxide yellow
(300mg & 400mg only), iron oxide red (400mg only) and black printing
ink SW-9008/SW-9009.
The black printing ink contains the following ingredients: shellac,
ethanol, isopropyl alcohol, tert-Butyl
alcohol, propylene glycol, ammonia, black iron oxide, potassium
hydroxide and purified water.
PHARMACOLOGY
PHARMACOLOGICAL ACTIONS
The mechanism by which gabapentin exerts its anticonvulsant action is
unknown. Gabapentin is
structurally related to the neurotransmitter GABA (gamma-aminobutyric
acid) but its mechanism of
action is different from that of several other medicines that interact
with GABA synapses including
valproate, barbiturates, benzodiazepines, GABA transaminase
inhibitors, GABA uptake inhibitors,
GABA agonists and GABA prodrugs. _In vitro_ studies with radiolabelled
gabapentin have characterised
a novel peptide binding site in rat brain tissues including neocortex
and hippocampus that may relate
to anticonvulsant activity of gabapentin and its structural
derivatives. However, the identification and
function of the gabapentin binding site remains to be elucidated.
Gabapentin at relevant clinical
concentrations does not bind to other common medicine or
neurotransmitter receptors of the brain
including GABA
A
, GABA
B
, benzodiazepine, glutamate, glycine or N-methyl-d-aspartate
receptors.
Gabapentin does not inter