देश: ऑस्ट्रेलिया
भाषा: अंग्रेज़ी
स्रोत: Department of Health (Therapeutic Goods Administration)
propofol, Quantity: 500 mg
Baxter Healthcare Pty Ltd
Propofol
Injection, emulsion
Excipient Ingredients: Soya Oil; glycerol; egg lecithin; sodium oleate; sodium hydroxide; water for injections
Intravenous
1 vial
(S4) Prescription Only Medicine
Short acting intravenous anaesthetic agent suitable for induction and maintenance of general anaesthesia in adults and children aged three years and older. Anesia1% has no analgesic properties. Although the safety and efficacy of propofol in paediatric day surgery have not been demonstrated, it may be a useful agent in this setting and its use should not be precluded. Anesia 1% may also be used in adults for sedation of ventilated patients receiving intensive care. Anesia 1% may also be used in adults for monitored conscious sedation for surgical and diagnostic procedures.
Visual Identification: White oil-in-water emulsion in a clear glass vial.; Container Type: Vial; Container Material: Glass; Container Life Time: 3 Years; Container Temperature: Store below 30 degrees Celsius
Registered
2009-05-22
ANESIA 1 % [Propofol] CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers some common questions about this medicine. It does not contain all the available information. It does not take the place of talking to your doctor or anaesthetist. All medicines have risks and benefits. Your doctor or anaesthetist has weighed the risks of you being given Anesia against the benefits it is expected to have for you. If you have any concerns about being given this medicine, ask your doctor or anaesthetist. Keep this leaflet. You may need to read it again. What Anesia is used for General anaesthesia Anesia contains propofol, which is used as a short-acting general anaesthetic in adults, and children aged 3 years or older. A general anaesthetic is a medicine which produces general anaesthesia. Anesia is short- acting, which means that patients go to sleep quickly, usually within 30 seconds of receiving the medication, but then wake up quickly as it wears off. Anesia can be used for very short operations when only one injection is needed. Anesia can be used throughout longer operations if more is given as repeated doses. Anesia can also be used to start off anaesthesia (induction anaesthesia). This means the anaesthetist may change over to another anaesthetic once sleep is induced. Sedation Anesia can be given to adults and adolescents over 16 years of age in lower doses if they need to be sedated or sleepy, but do not need the heavy sleep of anaesthesia. This type of sedation may be required during certain tests or procedures. Anesia can also be used in intensive care wards for adults and adolescents over 16 years of age who are being ventilated (on a breathing machine) to keep them sedated. Ask your doctor or anaesthetist if you have any questions about why this medicine has been prescribed for you. Your doctor or anaesthetist may have prescribed it for another reason. This medicine is not addictive. This medicine is available only with a doctor's prescription. There is not enough information to recommend पूरा दस्तावेज़ पढ़ें
PRODUCT INFORMATION Anesia Name of the drug Anesia is composed of:- Active: Propofol (10 mg/mL). Excipients: Soya oil (100 mg/mL), glycerol (22.5 mg/mL), egg lecithin (12 mg/mL), sodium oleate (0.3 mg/mL). Description Chemical name: 2,6-diisopropylphenol. Chemical structure: CAS: 2078-54-8. Molecular formula: C 12 H 18 O Molecular Weight: 178 Anesia is a white, oil in water emulsion in a clear glass vial. Pharmacology Pharmacodynamics: Propofol is a short acting general anaesthetic agent with a rapid onset of action of approximately 30 seconds. Recovery from anaesthesia is usually rapid. The mechanism of action, as for other general anaesthetics, is poorly understood. The majority of pharmacodynamic properties exhibited by propofol are proportional to the dose or concentration in the blood. These dose or dose rate dependent properties include the desired therapeutic effects of mild sedation through to anaesthesia, but also include the increasing incidence of cardiac and respiratory depression seen with increasing dose. The cardiovascular effects of propofol range from a minimal reduction in blood pressure through to arterial hypotension, and a decrease in heart rate. However, the haemodynamic parameters normally remain relatively stable during maintenance and the incidence of untoward haemodynamic changes is low. Although ventilatory depression can occur following administration of propofol, any effects are qualitatively similar to those of other intravenous anaesthetic agents and are readily manageable in clinical practice. It has been reported that in patients with normal intraocular pressure that propofol anaesthesia produces a decrease in intraocular pressure, which may be associated with a concomitant decrease in systemic vascular resistance. In combination with hypocarbia, propofol increases cerebrovascular resistance, decreases cerebral blood flow, cerebral metabolic oxygen consumption and intracranial pressure, but does not affect cerebrovascular reactivity to changes in arterial carbon dioxide tension. I पूरा दस्तावेज़ पढ़ें