PREFERIN - A TOPICAL OPHTHALMIC

Pays: Irlande

Langue: anglais

Source: HPRA (Health Products Regulatory Authority)

Ingrédients actifs:

MEPYRAMINE MALEATE PHENYLEPHRINE HYDROCHLORIDE

Disponible depuis:

Allergan Pharmaceuticals Ireland

Dosage:

0.12; 0.1 %w/v

forme pharmaceutique:

Eye Drops Solution

Date de l'autorisation:

1982-09-01

Résumé des caractéristiques du produit

PART II
SUMMARY OF PRODUCT CHARACTERISTICS
1 NAME OF THE MEDICINAL PRODUCT
PREFRIN-A Topical Ophthalmic Solution
2 QUALITATIVE AND QUANTITATIVE COMPOSITION
For excipients, see 6.1
3 PHARMACEUTICAL FORM
Eyedrops, solution
Topical, sterile ophthalmic solution
A clear and colourless solution.
4 CLINICAL PARTICULARS 
4.1 THERAPEUTIC INDICATIONS
PREFRIN-A is used in the symptomatic relief to eyes affected
with allergy/inflammation/irritation.
4.2 POSOLOGY AND METHOD OF ADMINSTRATION
Adults only: one to two drops may be repeated 3 to 4 hourly.
Method of Administration: topical into the conjunctival sac.
4.3 CONTRAINDICATIONS
Use in patients with a known hypersensitivity to any
of the active ingredients.
Use in patients with narrow angle glaucoma, or with
contact lenses.
Use in the presence of infections, foreign
bodies or where irritation is severe.
4.4 SPECIAL WARNINGS AND SPECIAL PRECAUTIONS FOR USE
Topical antihistamines are potential sensitizers and use may
produce a local sensitivity reaction.
Use with caution on an inflamed eye, as hyperaemia greatly
increases the rate of systemic absorption through the 
conjunctiva.
The puncta should be depressed after instillation of drops to
reduce drainage through the nasolacrimal duct to the oral 
and nasal mucosa.
If red eye persists, discontinue use and
consult the eye care specialist.
Active Ingredient
Phenylephrine hydrochloride
0.12 %w/v
Mepyramine maleate
0.10 %w/v
IRISH MEDICINES BOARD
________________________________________________________________________________________________________________________
_Date Issued 24/10/2005_
_CRN 2016030_
_page number: 1_
4.5 INTERACTION WITH OTHER MEDICINAL PRODUCTS AND OTHER FORMS OF INTERACTION 
Phenylephrine may increase the activity of:
Local anaesthetics
Adrenergic blockers
Monoamine oxidase inhibitors
Tricyclic antidepressants
Phenylephrine may decrease the activity of:
Local anae