PMS-METRONIDAZOLE CAPSULE

Pays: Canada

Langue: anglais

Source: Health Canada

Ingrédients actifs:

METRONIDAZOLE

Disponible depuis:

PHARMASCIENCE INC

Code ATC:

J01XD01

DCI (Dénomination commune internationale):

METRONIDAZOLE

Dosage:

500MG

forme pharmaceutique:

CAPSULE

Composition:

METRONIDAZOLE 500MG

Mode d'administration:

ORAL

Unités en paquet:

8/14/100

Type d'ordonnance:

Prescription

Domaine thérapeutique:

MISCELLANEOUS ANTIPROTOZOALS

Descriptif du produit:

Active ingredient group (AIG) number: 0102572003; AHFS:

Statut de autorisation:

APPROVED

Date de l'autorisation:

2006-08-31

Résumé des caractéristiques du produit

PRESCRIBING INFORMATION
PR
PMS-METRONIDAZOLE
Metronidazole Capsules, House Standard
500 mg
ANTIBACTERIAL - ANTIPROTOZOAL
PHARMASCIENCE INC.
Date of Revision:
April 13, 2018
6111 Royalmount Ave, Suite #100
Montréal, Canada
H4P 2T4
www.pharmascience.com
Control No. 214759
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PRESCRIBING INFORMATION
PR
PMS-METRONIDAZOLE
Metronidazole Capsules, House Standard
500 mg
THERAPEUTIC CLASSIFICATION
Antibacterial - Antiprotozoal
ACTION AND CLINICAL PHARMACOLOGY
pms-METRONIDAZOLE (metronidazole) is bactericidal against anaerobic
bacteria; it exerts
trichomonacidal activity and is also active against
_Giardia lamblia_
and
_Entamoeba histolytica_
. Its
exact mechanism of action has not been entirely determined as yet. It
has been proposed that an
intermediate in the reduction of metronidazole, produced only in
anaerobic bacteria and protozoa is
bound to deoxyribonucleic acid and electron-transport proteins,
inhibits subsequent nucleic acid
synthesis.
INDICATIONS AND CLINICAL USE
PMS-METRONIDAZOLE METRONIDAZOLE) IS INDICATED FOR THE TREATMENT OF:
PROTOZOAL INFECTIONS

Trichomonal infections in men as well as in women

Hepatic and intestinal amebiasis

Giardiasis
BACTERIAL VAGINOSIS
The “1988 Canadian Guidelines for the Treatment of Sexually
Transmitted Diseases in Neonates,
Children, Adolescents and Adults” recommends metronidazole for the
treatment of this condition.
BACTERIAL INFECTIONS
TREATMENT
Metronidazole is indicated in the treatment of serious anaerobic
intra-abdominal infections due to
susceptible anaerobic bacteria, such as
_Bacteroides fragilis _
(and other species of Bacteroides),
_Clostridium_
,
_Fusobacterium_
,
_Peptococcus_
, and
_Peptostreptococcus species_
. In the treatment of most
serious anaerobic infections, intravenous metronidazole is usually
administered initially. This may be
followed by oral therapy with pms-METRONIDAZOLE capsules at the
discretion of the physician.
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