PHESGO Combination for Subcutaneous Injection IN (フェスゴ配合皮下注IN)

Pays: Japon

Langue: anglais

Source: すりの適正使用協議会 RAD-AR Council, Japan

Ingrédients actifs:

Pertuzumab(genetical recombination); Trastuzumab(genetical recombination); Vorhyaluronidase alfa(genetical recombination)

Disponible depuis:

Chugai Pharmaceutical Co., Ltd.

DCI (Dénomination commune internationale):

Pertuzumab(genetical recombination); Trastuzumab(genetical recombination); Vorhyaluronidase alfa(genetical recombination)

forme pharmaceutique:

injection

Notice patient

Drug Information Sheet("Kusuri-no-Shiori")
Injection
Published: 11/2023
The information on this sheet is based on approvals granted by the
Japanese regulatory authority. Approval
details may vary by country. Medicines have adverse reactions (risks)
as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To
obtain a better therapeutic response,
patients should understand their medication and cooperate with the
treatment.
BRAND NAME:
PHESGO COMBINATION FOR SUBCUTANEOUS
INJECTION IN
ACTIVE INGREDIENT:
Pertuzumab(genetical recombination)
Trastuzumab(genetical recombination)
Vorhyaluronidase alfa(genetical recombination)
DOSAGE FORM:
injection
IMPRINT OR PRINT ON WRAPPING:
EFFECTS OF THIS MEDICINE
Pertuzumab (genetical recombination) and Trastuzumab (genetical
recombination) suppress
proliferation of cancer cells by selectively suppressing the actions
of protein named HER2
necessary for proliferation of cancer cells. Vorhyaluronidase alfa
(genetical recombination)
increases the subcutaneous tissue permeability by hydrolyzing
hyaluronic acid and promotes
the drug absorption.
It is usually used to treat breast cancer with HER2 positive and
HER2-positive unresectable
advanced or recurrent colorectal cancer progressing after cancer
chemotherapy.
THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS
MEDICINE.BE SURE TO TELL YOUR DOCTOR
AND PHARMACIST.
・If you have previously experienced any allergic reactions (itch,
rash, etc.) to any medicines
or foods.
If you have or have previously experienced heart disease.
If you are or have previously been treated with anthracycline
medicines.
If you are or have previously been treated with radiation therapy to
the chest.
If you have or have been previously diagnosed with hypertension.
・If you are pregnant, possibly pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may
interact to enhance or
diminish medicinal effects. Beware of over-the-counter medicines and
dietary supplements
as