Pays: États-Unis
Langue: anglais
Source: NLM (National Library of Medicine)
oxytetracycline hydrochloride (UNII: 4U7K4N52ZM) (oxytetracycline anhydrous - UNII:SLF0D9077S)
Norbrook Laboratories Limited
oxytetracycline hydrochloride
oxytetracycline hydrochloride 100 mg in 1 mL
INTRAVENOUS
PRESCRIPTION
A great many of the pathogens involved in cattle diseases are known to be susceptible to oxytetracycline hydrochloride therapy. Many strains of organisms, however, have shown resistance to oxytetracycline. In the case of certain coliforms, streptococci and staphylococci, it may be advisable to conduct culture and sensitivity testing to determine susceptibility of the infecting organism to oxytetracycline. In this manner, the likelihood of successful treatment with Oxytet 100 solution can be determined in advance.
Abbreviated New Animal Drug Application
OXYTET 100- OXYTETRACYCLINE HYDROCHLORIDE INJECTION, SOLUTION NORBROOK LABORATORIES LIMITED ---------- OXYTET 100 (OXYTETRACYCLINE INJECTION) ANTIBIOTIC EACH ML CONTAINS 100 MG OXYTETRACYCLINE HCL For use in Beef Cattle, Beef Calves, Non-lactating Dairy Cattle and Dairy Calves Only CAUTION: FEDERAL LAW RESTRICTS THIS DRUG TO USE BY OR ON THE ORDER OF A LICENSED VETERINARIAN. Each mL Contains: 100 mg oxytetracycline HCl,5.75% w/v magnesium chloride • 6 H2O, 17% v/v water for injection, 1.3% w/v sodium formaldehyde Sulfoxylate as a preservative and q.s. with propylene glycol. pH adjusted with monoethanolamine. DESCRIPTION Oxytet 100 (oxytetracycline injection) is a sterile ready-to-use preparation containing 100 mg/mL oxytetracycline HCl, for administration of the broad spectrum antibiotic, oxytetracycline, by injection. ANTIBIOTIC ACTION OF OXYTETRACYCLINE Oxytetracycline is effective against a wide range of gram-negative and gram-positive organisms that are pathogenic for cattle. The antibiotic is primarily bacteriostatic in effect, and is believed to exert its antimicrobial action by the inhibition of microbial protein synthesis. The antibiotic activity of oxytetracycline is not appreciably diminished in the presence of body fluids, serum or exudates. Since the drugs in the tetracycline class have similar antimicrobial spectra, organisms can develop cross resistance among them. Oxytetracycline is concentrated by the liver in the bile and excreted in the urine and feces at high concentrations and in a biologically active form. WARNING Discontinue treatment with Oxytet 100 at least 22 days prior to slaughter of the animal. This drug product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. CAUTION Rapid intravenous administration may result in Lire le document complet