CARBATOL 200 MG Comprimé

Pays: Tunisie

Langue: français

Source: Ministère de la Santé, Direction de l'inspection Pharmaceutique

Ingrédients actifs:

La CARBAMAZÉPINE

Disponible depuis:

Dar Al Dawa Development and Investment Co.Ltd

DCI (Dénomination commune internationale):

CARBAMAZEPINE

Dosage:

200 MG

forme pharmaceutique:

Comprimé

Unités en paquet:

B/30

classe:

C

Groupe thérapeutique:

ANTI-EPILEPTIQUES

Domaine thérapeutique:

SYSTEME NERVEUX

indications thérapeutiques:

- GRAND-MAL ASSOCIE OU NON A DES TROUBLES PSYCHIQUES. - EPILEPSIE PARTIELLE, EN PARTICULER EPILEPSIE PSYCHOMOTRICE DU LOBE TEMPORAL. - EPILEPSIE AVEC ATTEINTE PSYCHIQUE PREDOMINANTE. - TROUBLES CARACTERIELS INTERCRITIQUES. - TRAITEMENT DES NEVRALGIES FACIALES - PREVENTION DES RECHUTES MANIACODEPRESSIVES DANS LE CADRE DES PSYCHOSES MANIACODEPRESSIVES. - TRAITEMENT DES ETATS D'EXCITATION MANIAQUE.

Descriptif du produit:

Classement VEIC: Vital

Date de l'autorisation:

2002-01-24

Notice patient

DESCRIPTION:
CARBATOL
®
(carbamazepine) is an anticonvulsant agent.
Inactive Ingredients: Microcrystalline cellulose, silica colloidal
anhydrous, sodium starch glycolate, magnesium stearate, sodium
laurilsulfate.
PHARMACOLOGY:
The mechanism of action of carbamazepine, the active substance of
CARBATOL
®
, has not yet been fully elucidated. Carbamazepine
stabilizes hyperexcited nerve membranes, inhibits repetitive neuronal
discharges and reduces synaptic propagation of excitatory
impulses.
It is conceivable that inhibition of repetitive firing sodium
dependent action potentials in depolarized neurons via use and
voltage-
dependent blockade of sodium channels may be its main mechanism of
action. Whereas reduction of glutamate release and
stabilization of neuronal membranes may account mainly for the
antiepileptic activity of carbamazepine, the inhibitory effect on
dopamine and noradrenaline turnover may be responsible for its
antimanic properties.
INDICATIONS:
Epilepsy
-
Partial seizures (simple or complex, with or without loss of
consciousness), with or without secondary generalization.
-
Generalized tonic-clonic seizures.
-
Mixed forms of these seizures.
CARBATOL
®
is suitable for both monotherapy and combination therapy.
CARBATOL
®
is not normally effective in absence (petit mal) or in myoclonic
seizures.
Acute mania and maintenance treatment of bipolar affective disorders
to prevent or attenuate recurrence.
Alcohol-withdrawal syndrome.
Idiopathic trigeminal neuralgia and trigeminal neuralgia secondary to
multiple sclerosis (typical or atypical).
Idiopathic glossopharyngeal neuralgia.
CONTRAINDICATIONS:
Known hypersensitivity to carbamazepine and oxcarbazepine or
structurally related drugs (e.g. tricyclic antidepressants), or to
any of the other components of the formulation. Atrioventricular (AV)
block, history of bone-marrow depression or history of
acute intermittent porphyria. On the basis of its structural
similarity to tricyclic antidepressants, use of
CARBATOL
®
in combination
with monoamino-oxidase i