Aerrane 100ml 100%

Pays: Jordanie

Langue: anglais

Source: JFDA (Jordan Food & Drug Administration - المؤسسة العامة للغذاء والدواء)

Ingrédients actifs:

Isoflurane 100 %

Disponible depuis:

مستودع خوري - Khoury Drug Store

Code ATC:

N01AB06

DCI (Dénomination commune internationale):

Isoflurane 100 %

Dosage:

100%

Unités en paquet:

100ml

Fabriqué par:

BAXTER HEALTHCARE OF PUERTO RICO (امريكا)

Notice patient

AERRANE (isoflurane, USP) liquid for inhalation
DESCRIPTION
AERRANE (isoflurane, USP), a nonflammable liquid administered by
vaporizing, is a general
inhalation anesthetic drug. It is 1-chloro-2,2,2-trifluoroethyl
difluoromethyl ether, and its structural
formula is:
Some physical constants are:
Molecular weight
184.5
Boiling point at 760 mm Hg
48.5°C (uncorr.)
Refractive index n20
D
1.2990-1.3005
Specific gravity 25°/25°C
1.496
Vapor pressure in mm Hg**
20°C
238
25°C
295
30°C
367
35°C
450
**Equation for vapor pressure calculation:
log10Pvap =
A + B where
A = 8.056
T
B = -1664.58
T = °C + 273.16 (Kelvin)
Partition coefficients at 37°C:
Water/gas
0.61
Blood/gas
1.43
Oil/gas
90.8
Partition coefficients at 25°C – rubber and plastic
Conductive rubber/gas
62.0
Butyl rubber/gas
75.0
Polyvinyl chloride/gas
110.0
Polyethylene/gas
~2.0
Polyurethane/gas
~1.4
Polyolefin/gas
~1.1
Butyl acetate/gas
~2.5
Purity by gas
chromatography
>99.9%
Lower limit of
flammability in oxygen
or nitrous oxide at 9
joules/sec. and 23°C
None
Lower limit of
flammability in oxygen
or nitrous oxide at 900
joules/sec. and 23°C
Greater than useful concentration in
anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no
additives or chemical stabilizers.
Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored
in indirect sunlight in clear,
colorless glass for five years, as well as samples directly
exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V.
light were unchanged in
composition as determined by gas chromatography. Isoflurane in one
normal sodium methoxide-
methanol solution, a strong base, for over six months consumed
essentially no alkali, indicative of
strong base stability. Isoflurane does not decompose in the presence
of soda lime (at normal operating temperatures), and does not attack
aluminum, tin, brass, iron or
copper.
CLINICAL PHARMACOLOGY
Induction of and recovery from isoflurane anesthesia are rapid.
Isoflurane has a mild pungency
which limits the rate of induction, althoug