Zetril Powder 1500mg

Maa: Malesia

Kieli: englanti

Lähde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktiivinen ainesosa:

Glucosamine Sulfate Sodium Chloride

Saatavilla:

IMEKS PHARMA SDN. BHD.

INN (Kansainvälinen yleisnimi):

Glucosamine Sulfate Sodium Chloride

Kpl paketissa:

15Units Units; 25Units Units; 50Units Units; 60Units Units; 10Units Units; 30Units Units; 40Units Units; 100Units Units; 5Units Units; 12Units Units; 20Units Units

Valmistaja:

T.O. PHARMA CO., LTD.

Pakkausseloste

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
ZETRIL POWDER
®
Glucosamine Sulphate (1500mg)
1
WHAT IS IN THE LEAFLET
1.
What Zetril is used for
2.
How Zetril works
3.
Before you use Zetril
4.
How to use Zetril
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Zetril
8.
Product Description
9.
Manufacturer and Product Registration
Holder
10.
Date of Revision
WHAT ZETRIL
IS USED FOR
Zetril contains 1500mg of Glucosamine
Sulphate as the active ingredient.
Zetril is a supplement used to relieve the
symptoms of osteoarthritis.
HOW ZETRIL
WORKS
It works by reducing joint pains and
improving joint functions, thus preserving
joints and prevent early onset of arthritis.
BEFORE YOU USE ZETRIL_ _
-
_When you must not use it_
• Hypersensitive to Glucosamine or any other
ingredients in Zetril
• Allergic to shellfish or shellfish derived
products
-
_Before you start to use it_
Tell your doctor if you:
• Have diabetes
• Have peptic ulcers
• Are inherited with Phenylketonuria
(disorder that causes build-up of
phenylalanine in the body)
• Have severe liver or kidney problem
Effect can only be seen after approximately 1
week from the beginning. Therefore, in case
of intense pains, it is advisable to take pain
reliever as recommended by doctor during
the first days of treatment with Zetril.
If you are not sure whether you should start
taking this product, consult your doctor.
-
_Taking other medicines_
Tell your doctor if you are taking any other
medicine, including any that you buy without
a prescription. You may need to use different
amounts of these medicines, or you may
need to take different medicines. Your doctor
will advise you. In particular, tell your doctor
if you take any of the following:
• Antidiabetic agent
• Warfarin (medicines used to prevent blood
clotting)
_Pregnancy and lactation _
Ask your doctor or pharmacist for advice
before taking any medicine.
Your doctor will discuss the risk and benefit
of taking Zetril during pregnancy and
breastfeeding.
HOW TO USE ZETRIL
Always tak

Valmisteyhteenveto

DESCRIPTION
White granules.
The product contains no flavouring and the taste is slightly sweet
nd sour.
a
CONTENTS
Each _ ZE_
_TRIL POWDER 1500MG_ 3.95g sac
het contains Glucosamine
Sulphate Sodium Chloride 1884.00mg (equivalent to Glucosamine
Sulphate 1500.00mg.)
Excipients: Sorbitol, Aspartame, Citric acid and Polyethylene Glycol
000
6
PROPERTIES
Glucosamine
possesses
arthrotrophic
metabolic
activity
by
st
imulat
ing the anabolic metabolism of osteocartilageneous tissues
via
stimulation
of
the
biosynthesis
of
the
mucopolysaccharides
(which
are
the
essential
components
of
the
cartilage
ground-
bstances) and of the bone mesenchymal tissues.
su
Glucosamine also acts to improve the viscosity of synovial fluid by
increasing synovial fluid production, thereby providing lubricant
ctivity.
a
Glucosamine is therapeutically used in all forms of degenerative
osteoarticul
ar
disease
such
as
arthrosis
and
osteoarthritis
(both
subacute
and
chronic)
with
the
following
therapeutic
effects:
disappearance or reduction of articular pains, improvement of
articular
function,
inhibition
of
regression
of
the
degenerative
rocess.
p
PHARMACOKINETICS
Glucosamine is highly absorbable in the sulphate form and the
sulph
ate component appears to potentiate the therapeutic effect
f glucosamine therapy.
o
Pharmacokinetic studies show that glucosamine sulphate when
t
aken orally,
is well absorbed from the digestive tract at a rate
approaching 90% and from there it is transported via the portal
circulation to the liver. It appears that a significant fraction of
the
ingested glucosamine is catabolised by first-pass metabolism in the
liver. Some uptake in the articular cartilage is seen in animal
studies.
ee glucosamine is not detectable in plasma.
Fr
Elimination of glucosamine is primarily through the urine, with a
small a
mount of glucosamine or its derivatives eliminated in the
faeces.
The
elimination
half-life
of
glucosamine,
which
is
incorporated into the plasma proteins, is about 68 hours after oral
oses.
d
INDICATIONS
_ZETRIL _
_POWDER _
_